Protein Alignment NR2F1 and usp

DIOPT Version :10

• Sequence 1: NP_005645.1
• Gene: NR2F1 / 7025
• HGNCID: 7975
• Length: 423
• Species: Homo sapiens
• Sequence 2: NP_476781.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Alignment Length: 463
• Identity: 147/463 - (31%)
• Similarity: 207/463 - (44%)
• Gaps: 102/463 - (22%)

Human    25 PAAQAARGGGGGAGEQQQQAGSGAPHTPQTPGQPGAPATPGTAGDKGQGPPGSGQSQQHIECVVC 89
            |.:.:|......||:.|.         .|.|...|..|   .|..:.|.||....|.....|.:|
  Fly    55 PGSNSASSNNNSAGDAQM---------AQAPNSAGGSA---AAAVQQQYPPNHPLSGSKHLCSIC 107

Human    90 GDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRRE 154
            ||::||||||.::|||||.||||:||::|||.||.||||.||:..||:|||||.:|||..||:||
  Fly   108 GDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACRENRNCIIDKRQRNRCQYCRYQKCLTCGMKRE 172

Human   155 AVQRGRMPPTQPNPGQYALTNGDPL--------------------------NG-HCYLSGYIS-- 190
            |||..|....:...|:.:.:.|...                          || ..:::..:|
  Fly   173 AVQEERQRGARNAAGRLSASGGGSSGPGSVGGSSSQGGGGGGGVSGGMGSGNGSDDFMTNSVSRD 237

Human   191 ----------------------LLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEW 233
                                  ..||..||.|       :||:....:..:|::..:.||..||:
  Fly   238 FSIERIIEAEQRAETQCGDRALTFLRVGPYST-------VQPDYKGAVSALCQVVNKQLFQMVEY 295

Human   234 ARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSM----------------------------- 269
            ||.:|.|..:.:.|||.||:..|.||.:.|.|.||:
  Fly   296 ARMMPHFAQVPLDDQVILLKAAWIELLIANVAWCSIVSLDDGGAGGGGGGLGHDGSFERRSPGLQ 360

Human   270 PLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACG 334
            |..:. |..:...|.:......|.|..|  ||..|...|:|.|::|..|.||||||:|:..|..|
  Fly   361 PQQLF-LNQSFSYHRNSAIKAGVSAIFD--RILSELSVKMKRLNLDRRELSCLKAIILYNPDIRG 422

Human   335 LSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPI 399
            :...|.||..:||....|:|:.|.::|....||.:||||||:||::|....:.||..|:....|:
  Fly   423 IKSRAEIEMCREKVYACLDEHCRLEHPGDDGRFAQLLLRLPALRSISLKCQDHLFLFRITSDRPL 487

Human   400 ETLIRDML 407
            |.|..:.|
  Fly   488 EELFLEQL 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NR2F1	NP_005645.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..81		13/55 (24%)
		NR_DBD_COUP_TF	86..158	CDD:143516	48/71 (68%)
		NR_LBD_COUP-TF	184..419	CDD:132746	79/277 (29%)
usp	NP_476781.1	NR_DBD_RXR	102..178	CDD:143514	49/75 (65%)
		NR_LBD_RXR_like	237..480	CDD:132741	73/252 (29%)