Protein Alignment TFAM and TFAM

DIOPT Version :10

• Sequence 1: NP_003192.1
• Gene: TFAM / 7019
• HGNCID: 11741
• Length: 246
• Species: Homo sapiens
• Sequence 2: NP_732527.1
• Gene: TFAM / 42433
• FlyBaseID: FBgn0038805
• Length: 284
• Species: Drosophila melanogaster
• Alignment Length: 194
• Identity: 66/194 - (34%)
• Similarity: 111/194 - (57%)
• Gaps: 19/194 - (9%)

Human    50 PKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPDSKKKIYQDAYRAEWQVYKEEI 114
            ||||::.|.||.:||.|..||.||...|.|::|::::.|.:.....|:..|..::.:.|:|.||.
  Fly    78 PKKPLTPYFRFMREQRPKLKAANPQITTVEVVRQLSKNWSDADAQLKERLQAEFKRDQQIYVEER 142

Human   115 SRFKEQLTPSQ---IMSLEKEIMDKHLKRKAMTKKKELTLLGKPKRPRSAYNVYVA-ERFQEAKG 175
            :::...||..|   |..|:::::|...:|:...:.||   ||:||:|.||:..::| ||....:|
  Fly   143 TKYDATLTEEQRAEIKQLKQDLVDAKERRQLRKRVKE---LGRPKKPASAFLRFIASERINTPQG 204

Human   176 DSPQEKLKTVKE-------NWKNLSDSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLR 232
            |.     :|.:|       .|..|||||||:|:|.::::...|...:..|||:||.:|..|::|
  Fly   205 DK-----QTYREWHQKTTAKWTRLSDSEKEVYMQESRKEMELYRKAISVWEEKMIRLGHIDVVR 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TFAM	NP_003192.1	HMG-box_TFAM_rpt1	50..115	CDD:438802	24/64 (38%)
		HMG-box_TFAM_rpt2	135..234	CDD:438803	37/106 (35%)
TFAM	NP_732527.1	HMG-box_SF	78..138	CDD:469606	21/59 (36%)
		HMG-box_SF	168..263	CDD:469606	36/101 (36%)