Protein Alignment TFAM and Hmg-2

DIOPT Version :10

• Sequence 1: NP_003192.1
• Gene: TFAM / 7019
• HGNCID: 11741
• Length: 246
• Species: Homo sapiens
• Sequence 2: NP_611553.1
• Gene: Hmg-2 / 37407
• FlyBaseID: FBgn0026582
• Length: 376
• Species: Drosophila melanogaster
• Alignment Length: 142
• Identity: 39/142 - (27%)
• Similarity: 70/142 - (49%)
• Gaps: 11/142 - (7%)

Human    46 LASCPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPDSKKKIYQDAYRAEWQVY 110
            :|..||.|::.|:||..::....:.:.|.....|..|.|.:.|.:||:.:|..|.:|...:..:|
  Fly    72 VAGAPKMPLNGYVRFMNDRREELRREQPQRTALEHTRIIGEEWHQLPEERKLPYIEAAAKDKAIY 136

Human   111 KEEISRF-KE--QLTPSQIMSLEKEI-MDKHLKRKAMTKKKELTLLGKPKRPRSAYNVYVAERFQ 171
            :|::..| ||  ::..:::...:|.. :|...|.|  |.|.| :.|||.|:.::.    ..:|..
  Fly   137 QEQLQMFLKEHPEIVANELAKAKKATKLDGSPKEK--TPKGE-SALGKAKKTKAK----PVKRQS 194

Human   172 EAKGDSPQEKLK 183
            |...|.|..|:|
  Fly   195 EDPDDVPLAKVK 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TFAM	NP_003192.1	HMG-box_TFAM_rpt1	50..115	CDD:438802	18/64 (28%)
		HMG-box_TFAM_rpt2	135..234	CDD:438803	16/49 (33%)
Hmg-2	NP_611553.1	HMG-box_HMG20	75..154	CDD:438796	21/78 (27%)