Protein Alignment TFAM and Dsp1

DIOPT Version :10

• Sequence 1: NP_003192.1
• Gene: TFAM / 7019
• HGNCID: 11741
• Length: 246
• Species: Homo sapiens
• Sequence 2: NP_001138203.1
• Gene: Dsp1 / 117294
• FlyBaseID: FBgn0278608
• Length: 397
• Species: Drosophila melanogaster
• Alignment Length: 177
• Identity: 38/177 - (21%)
• Similarity: 77/177 - (43%)
• Gaps: 23/177 - (12%)

Human    50 PKKPVSSYLRFSKEQLPIFKAQNPDAKT--TELIRRIAQRWRELPDSKKKIYQDAYRAEWQVYKE 112
            |:..:::|..|.:......|.::||...  .|..|:.|:||:.:.|.:||.:.:....:.|.|:.
  Fly   183 PRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYEA 247

Human   113 EISRFKEQLTP-SQIMSLEKEIMDKHLKRKAMTKKKELTLLGKPKRPRSAYNVYVAERFQEAKGD 176
            |:..:   :.| ..::...|             |:|::.....|||..||:..:..:...:.|..
  Fly   248 EMQNY---VPPKGAVVGRGK-------------KRKQIKDPNAPKRSLSAFFWFCNDERNKVKAL 296

Human   177 SPQ----EKLKTVKENWKNLSDSEKELYIQHAKEDETRYHNEMKSWE 219
            :|:    :..|.:...|.::....|:.|...|:.|:.||..||..::
  Fly   297 NPEFGVGDIAKELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYK 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TFAM	NP_003192.1	HMG-box_TFAM_rpt1	50..115	CDD:438802	17/66 (26%)
		HMG-box_TFAM_rpt2	135..234	CDD:438803	19/89 (21%)
Dsp1	NP_001138203.1	HMG-box_HMGB_rpt1	182..250	CDD:438794	17/66 (26%)
		HMG-box_NHP6-like	262..342	CDD:438792	20/92 (22%)