Protein Alignment TEAD3 and sd

DIOPT Version :10

• Sequence 1: NP_003205.2
• Gene: TEAD3 / 7005
• HGNCID: 11716
• Length: 435
• Species: Homo sapiens
• Sequence 2: NP_001368984.1
• Gene: sd / 32536
• FlyBaseID: FBgn0003345
• Length: 747
• Species: Drosophila melanogaster
• Alignment Length: 436
• Identity: 246/436 - (56%)
• Similarity: 293/436 - (67%)
• Gaps: 88/436 - (20%)

Human    13 GEAREDGPEGLDKGLDN-DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARY 76
            |:..:|     :|.|.: ||||||||||||||||||:||||||||||||||||||||||||||||
  Fly    75 GDMSDD-----EKDLSSADAEGVWSPDIEQSFQEALSIYPPCGRRKIILSDEGKMYGRNELIARY 134

Human    77 IKLRTGKTRTRKQVSSHIQVLARKKVREYQVGIKAMNLDQVSKDKALQSMASMSSAQIVSASVLQ 141
            |||||||||||||||||||||||:|:||.|..||.
  Fly   135 IKLRTGKTRTRKQVSSHIQVLARRKLREIQAKIKV------------------------------ 169

Human   142 NKFSPPSPLPQAVFSTSSRFWSSPPLLGQQPGPSQDIKPFAQPAYPI----------QPPLPPTL 196
                              :||..    |.||..|||||||.||.||.          :..:||
  Fly   170 ------------------QFWQP----GLQPSTSQDIKPFPQPPYPAGKTSTAVSGDETGIPP-- 210

Human   197 SSYEPLAPLPSAAASVPVWQDRTIASSRLRLLEYSAFMEVQRDPDTYSKHLFVHIGQTNPAFSDP 261
                  :.||        |:.|.||:.:.||||::||||:||| :.|.:||||.:| ..|:||||
  Fly   211 ------SQLP--------WEGRAIATHKFRLLEFTAFMEIQRD-EIYHRHLFVQLG-GKPSFSDP 259

Human   262 PLEAVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWADLNSTIQEG--PGAFYGVSSQYSSA 324
            .||.||:|||:||||||.||||:||||||.|||:|||.|||||:.:..|  .|.||||:|||.|.
  Fly   260 LLETVDIRQIFDKFPEKSGGLKDLYEKGPQNAFYLVKCWADLNTDLTTGSETGDFYGVTSQYESN 324

Human   325 DSMTISVSTKVCSFGKQVVEKVETEYARLENGRFVYRIHRSPMCEYMINFIHKLKHLPEKYMMNS 389
            :::.:..||.|||||||||||||:||:||||.|:||||.||||||||||||.|||:|||:|||||
  Fly   325 ENVVLVCSTIVCSFGKQVVEKVESEYSRLENNRYVYRIQRSPMCEYMINFIQKLKNLPERYMMNS 389

Human   390 VLENFTILQVVTSRDSQETLLVIAFVFEVSTSEHGAQHHVYKLVKD 435
            ||||||||||:.:|::|||||.||:||||:....|..||:|:|:|:
  Fly   390 VLENFTILQVMRARETQETLLCIAYVFEVAAQNSGTTHHIYRLIKE 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TEAD3	NP_003205.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34		7/21 (33%)
		TEA	30..97	CDD:128703	65/66 (98%)
		Transcriptional activation. /evidence=ECO:0000255	173..435		161/273 (59%)
		YBD	223..432	CDD:435993	141/210 (67%)
sd	NP_001368984.1	TEA	88..155	CDD:128703	65/66 (98%)
		YBD	224..432	CDD:435993	141/209 (67%)