Protein Alignment ACTC1 and Arp1

DIOPT Version :10

• Sequence 1: NP_005150.1
• Gene: ACTC1 / 70
• HGNCID: 143
• Length: 377
• Species: Homo sapiens
• Sequence 2: NP_524331.2
• Gene: Arp1 / 41566
• FlyBaseID: FBgn0011745
• Length: 376
• Species: Drosophila melanogaster
• Alignment Length: 370
• Identity: 201/370 - (54%)
• Similarity: 271/370 - (73%)
• Gaps: 7/370 - (1%)

Human    10 LVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIE 74
            :|.|||||::||||||:..|:..||:.:|||:|..||.|..:.|.:||.:|:..||:|:::||:|
  Fly    12 VVIDNGSGVIKAGFAGEHIPKCRFPNYIGRPKHVRVMAGALEGDIFVGPKAEEHRGLLSIRYPME 76

Human    75 HGIITNWDDMEKIWHHTFYNE-LRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAI 138
            |||:|:|:|||:||.:.:..| |....|:||.|||||||||:.||||..:..||..|.||::|::
  Fly    77 HGIVTDWNDMERIWSYIYSKEQLATFTEDHPVLLTEAPLNPRRNREKAAEFFFEGINAPALFVSM 141

Human   139 QAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFV 203
            ||||||||:||.||:||||||||||.||||||:|:||:|||:|:||||:|.||..::...|::|.
  Fly   142 QAVLSLYATGRVTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVTRYLKTLIRREGFNFR 206

Human   204 TTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEK-SYELPDGQVITIGNERFRCPETLFQPS 267
            :|||.||||.||||:||:|.:.:.|     .:...|| :|:||||::..||..|||.||.||:|.
  Fly   207 STAEFEIVRSIKEKVCYLATNPQKE-----ETVETEKFAYKLPDGKIFEIGPARFRAPEVLFRPD 266

Human   268 FIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKII 332
            .:|.|..|||:....||.|.|:|:||.||.|.|||||:|::.|..||:..|:...:...:||:|.
  Fly   267 LLGEECEGIHDVLMYSIEKSDMDLRKMLYQNIVLSGGSTLFKGFGDRLLSELKKHSAKDLKIRIA 331

Human   333 APPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF 377
            ||.||.||.|:||||||||.||::|||||:||:|.|...||||.|
  Fly   332 APQERLYSTWMGGSILASLDTFKKMWISKREYEEEGQKAVHRKTF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACTC1	NP_005150.1	ASKHA_NBD_actin	8..372	CDD:466823	196/363 (54%)
Arp1	NP_524331.2	ASKHA_NBD_Arp1	9..375	CDD:466820	199/367 (54%)