Protein Alignment ACTC1 and Arp53D

DIOPT Version :10

• Sequence 1: NP_005150.1
• Gene: ACTC1 / 70
• HGNCID: 143
• Length: 377
• Species: Homo sapiens
• Sequence 2: NP_477037.2
• Gene: Arp53D / 36879
• FlyBaseID: FBgn0011743
• Length: 411
• Species: Drosophila melanogaster
• Alignment Length: 369
• Identity: 236/369 - (63%)
• Similarity: 290/369 - (78%)
• Gaps: 5/369 - (1%)

Human     9 ALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPI 73
            |:|.|||||:.||||:.:|.||||||||||||||..|::.....||.:|:.|..|||||||||||
  Fly    48 AVVIDNGSGVCKAGFSPEDTPRAVFPSIVGRPRHLNVLLDSVIGDSVIGEAAARKRGILTLKYPI 112

Human    74 EHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAI 138
            |||::.|||:||.:|.|| |..||..|.:.|.||||||||||.||||||:||||.|.|||.|||:
  Fly   113 EHGMVKNWDEMEMVWQHT-YELLRADPMDLPALLTEAPLNPKKNREKMTEIMFEHFQVPAFYVAV 176

Human   139 QAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFV 203
            ||||||||:|||.|||:||||||||.||||||:|||||.:|:|||||||||||.|:|.|||.:..
  Fly   177 QAVLSLYATGRTVGIVVDSGDGVTHTVPIYEGFALPHACVRVDLAGRDLTDYLCKLLLERGVTMG 241

Human   204 TTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSF 268
            |:|||||||:||||||||::::..||    ......::|||||||.|.:|.|||||||.|||||.
  Fly   242 TSAEREIVREIKEKLCYVSMNYAKEM----DLHGKVETYELPDGQKIVLGCERFRCPEALFQPSL 302

Human   269 IGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIA 333
            :|.|..||||.|::||..||:|:|||:|||.||||||||:..|..|..:::|.:||.:::||:.|
  Fly   303 LGQEVMGIHEATHHSITNCDMDLRKDMYANIVLSGGTTMFRNIEHRFLQDLTEMAPPSIRIKVNA 367

Human   334 PPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF 377
            .|:|::|||.|||:||||::||.|||...||:|.|.:|||||||
  Fly   368 SPDRRFSVWTGGSVLASLTSFQNMWIDSLEYEEVGSAIVHRKCF 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACTC1	NP_005150.1	ASKHA_NBD_actin	8..372	CDD:466823	229/362 (63%)
Arp53D	NP_477037.2	ASKHA_ATPase-like	47..406	CDD:483947	229/362 (63%)