DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment BTN1A1 and dpr11

DIOPT Version :9

Sequence 1:	NP_001723.2	Gene:	BTN1A1 / 696	HGNCID:	1135	Length:	526	Species:	Homo sapiens
Sequence 2:	NP_001262320.1	Gene:	dpr11 / 40800	FlyBaseID:	FBgn0053202	Length:	360	Species:	Drosophila melanogaster

Alignment Length:	308	Identity:	69/308 - (22%)
Similarity:	107/308 - (34%)	Gaps:	87/308 - (28%)

- Green bases have known domain annotations that are detailed below.

Human     5 PSSGLPRCLLTLILLQLPKLDSAPFDVIGPPEPIL---------AVVGEDAELPCRLSP--NASA 58
            |||......|..:...||:. ||.....|..||.|         ..:|..|.||||:..  |.|
  Fly    86 PSSATAFSSLAQVSSLLPEA-SALSATSGLVEPYLDGYATSNVTTQIGTHAYLPCRVKQLGNKS- 148

Human    59 EHLELRWFRKKVSPAVLVHR-----DGREQEAEQMPEYRGRATLVQDGIAKGRVALRIRGVRVSD 118
                :.|.|.:....:.|.|     |.|....:|..:|               ..|:|:.|:..|
  Fly   149 ----VSWIRLRDGHILTVDRAVFIADQRFLAIKQPDKY---------------WTLQIKYVQARD 194

Human   119 DGEYTCFFREDGSYEEALVHLKVAA-----LGSDPHISMQVQENGEICLEC---------TSVGW 169
            .|.|.|....:... .|.|.|:|..     || :|  ...|:....:.|.|         |.:.|
  Fly   195 AGSYECQVSTEPKV-SARVQLQVVVPRTEILG-EP--DRYVKAGSNVVLRCIVRGALEPPTFIMW 255

Human   170 YPEPQV------QWRTSKGEKFPSTSESRNPDEEGLFTVAASVI----IRDTSAKNVSC------ 218
            |...:.      :.||......|..|      .||..|:.:.:|    .|||.  |.:|
  Fly   256 YHGAEQLAADSRRHRTQLDPNLPEAS------GEGQSTIGSLIIESAKKRDTG--NYTCSPSNSP 312

Human   219 ---YIQNLLLGQEKKVEISIPASSLPRLTPWIVAVAVILMVLGLLTIG 263
               ...|::.|:.....::..|:     |....|::::.::|.::.||
  Fly   313 SATVTLNIINGESSASAVTSSAA-----TTRAYALSILALLLSVILIG 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BTN1A1	NP_001723.2	IG_like	35..141	CDD:214653	29/121 (24%)
		Ig_MOG_like	43..142	CDD:143190	26/105 (25%)
		Ig	162..223	CDD:299845	18/88 (20%)
		SPRY_PRY_BTN1_2	302..473	CDD:293991
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	495..526
dpr11	NP_001262320.1	I-set	125..216	CDD:254352	26/111 (23%)
		Ig	127..217	CDD:299845	26/110 (24%)
		IG_like	227..320	CDD:214653	20/102 (20%)
		IGc2	234..311	CDD:197706	18/84 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910