DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BTN1A1 and dpr7

DIOPT Version :9

Sequence 1:	NP_001723.2	Gene:	BTN1A1 / 696	HGNCID:	1135	Length:	526	Species:	Homo sapiens
Sequence 2:	NP_001096850.2	Gene:	dpr7 / 2768865	FlyBaseID:	FBgn0053481	Length:	312	Species:	Drosophila melanogaster

Alignment Length:	307	Identity:	65/307 - (21%)
Similarity:	103/307 - (33%)	Gaps:	104/307 - (33%)

- Green bases have known domain annotations that are detailed below.

Human    16 LILLQLPKLDSAPFDVIGPPEPILAVVGEDAELPCRLSPNASAEHLELRWFRKKVSPAV------ 74
            |.|..|..|:...||.|. |..:.|||.|.|.|.||:....:.   .:.|.||:....:
  Fly    40 LSLNDLTNLERPFFDDIS-PRNVSAVVDEIAILRCRVKNKGNR---TVSWMRKRDLHILTTNIYT 100

Human    75 --------LVHRDGREQEAEQMPEYRGRATLVQDGIAKGRVALRIRGVRVSDDGEYTCFFREDGS 131
                    ::|..|.|.                       ..|:|...:..|.|.|.|....:..
  Fly   101 YTGDQRFSVIHPPGSED-----------------------WDLKIDYAQPRDSGVYECQVNTEPK 142

Human   132 YEEALVHLKVAA-----------------------LGSDPHISMQVQENGEICLECT------SV 167
            ...|:. |:|.|                       |||   ..:.|:.:..|.|.|:      ||
  Fly   143 INLAIC-LQVIADNDFQDLKTKKRFYDTKSARAKILGS---TEIHVKRDSTIALACSVNIHAPSV 203

Human   168 GWY-PEPQVQWRTSKG------EKFPSTSESRNPDEEGLFTVAASVIIRDTSAKNVSCYIQNLLL 225
            .|| ....|.:.:.:|      ||....:.||      |....||  :||:.  |.:| :.|..:
  Fly   204 IWYHGSSVVDFDSLRGGISLETEKTDVGTTSR------LMLTRAS--LRDSG--NYTC-VPNGAI 257

Human   226 GQEKKVEI-------SIPASSLPRLTPW-----IVAVAVILMVLGLL 260
            ....:|.:       ::..||..|:..:     |::..|:|.:..|:
  Fly   258 PASVRVHVLTGEQPAAMQTSSAIRIRAFTAMITIISTKVLLYISSLM 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BTN1A1	NP_001723.2	IG_like	35..141	CDD:214653	23/119 (19%)
		Ig_MOG_like	43..142	CDD:143190	19/112 (17%)
		Ig	162..223	CDD:299845	19/73 (26%)
		SPRY_PRY_BTN1_2	302..473	CDD:293991
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	495..526
dpr7	NP_001096850.2	V-set	56..145	CDD:284989	22/115 (19%)
		IG_like	58..140	CDD:214653	21/107 (20%)
		IG_like	179..265	CDD:214653	24/99 (24%)
		Ig	187..257	CDD:299845	21/80 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910