DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment BTN1A1 and fsn-1

DIOPT Version :9

Sequence 1:	NP_001723.2	Gene:	BTN1A1 / 696	HGNCID:	1135	Length:	526	Species:	Homo sapiens
Sequence 2:	NP_498046.1	Gene:	fsn-1 / 175667	WormBaseID:	WBGene00001499	Length:	332	Species:	Caenorhabditis elegans

Alignment Length:	334	Identity:	58/334 - (17%)
Similarity:	97/334 - (29%)	Gaps:	140/334 - (41%)

- Green bases have known domain annotations that are detailed below.

Human   178 RTSKGEKFPSTSESRNPDEEGLFTVAASVIIRDTSAKNVSCYIQNLLLGQE----------KKV- 231
            |..:..:.|..|.||.| .:.|..:...:.::|..:..::|:..|..|..|          ||:
Worm    70 RRRRSPRRPEVSASRLP-LKVLNQIFQYLPLKDLRSAMLTCHSWNNALSMEDSDIWQYLLGKKLP 133

Human   232 --EISIP------ASSLPRLTPWIVAVAVILMVLGLLTIGSIFFTWRLYNERPRERRNEFSSKER 288
              .:|.|      .|:..:|..|                   :|.|   |.....|.|
Worm   134 EAAVSDPFLLAELGSAKKKLRAW-------------------YFAW---NTSDISRNN------- 169

Human   289 LLEELKWKKATLHAVDVTLDPDTAHPHLFLYEDSKSVRLEDSRQKLPEKTERFDSWPCVLGRETF 353
               .::....|:|                             ||.:.:.|:.      |.|:...
Worm   170 ---YIRTNGFTVH-----------------------------RQPVAQSTDG------VRGKRGI 196

Human   354 TSGRHYWEVE----------VGDRTDWAIGVCRENVMKKGFDPMTPENGFWA------VELYGNG 402
            :.|.|.:::.          ||..|..|...|...|...|.|..:     |.      |.::...
Worm   197 SKGVHAFDITWDGPLGTVAVVGIATKHAALHCVGYVALLGSDDQS-----WGWNLVDNVLMHNGA 256

Human   403 YWALTPLRTPLPLAGPPRRVGIFLDYESGD-----------ISFYNMNDGSDIYTFSNVTFS--G 454
            ...:.|     .:..||:       ||.||           ::::..|.     .|..:.|:  .
Worm   257 QLGVYP-----KMNNPPK-------YEVGDKIRLIIDCDTHVAYFERNS-----EFLGIAFNHIP 304

Human   455 PLR--PFFC 461
            |||  |..|
Worm   305 PLRLYPAVC 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BTN1A1	NP_001723.2	IG_like	35..141	CDD:214653
		Ig_MOG_like	43..142	CDD:143190
		Ig	162..223	CDD:299845	9/44 (20%)
		SPRY_PRY_BTN1_2	302..473	CDD:293991	32/191 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	495..526
fsn-1	NP_498046.1	F-box	83..127	CDD:279040	9/44 (20%)
fsn-1	NP_498046.1	SPRY_Fbox	158..332	CDD:293964	39/226 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910