Protein Alignment BTK and skb5

DIOPT Version :9

• Sequence 1: NP_001274273.1
• Gene: BTK / 695
• HGNCID: 1133
• Length: 693
• Species: Homo sapiens
• Sequence 2: NP_588016.1
• Gene: skb5 / 2539237
• PomBaseID: SPCC24B10.13
• Length: 140
• Species: Schizosaccharomyces pombe
• Alignment Length: 65
• Identity: 24/65 - (36%)
• Similarity: 35/65 - (53%)
• Gaps: 4/65 - (6%)

Human   240 PAAAPVSTSELKKVVALYDYMPMNANDLQLRKGDEYFILEESNLPWWRA-RDKNGQEGYIPSNYV 303
            |:|   |.:.|...|||||:.|::.|:|....|....||.||:..|..| .|.:|:.|.:|..:|
pombe    75 PSA---SFNVLADAVALYDFEPLHDNELGFTTGQRLCILSESSDGWLIAYDDASGRSGLVPETFV 136

Human   304  303
            pombe   137  136

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BTK	NP_001274273.1	PH	38..167	CDD:278594
		PH_Btk	40..200	CDD:269944
		SH3_BTK	251..305	CDD:212839	20/54 (37%)
		SH2_Tec_Btk	308..413	CDD:198260
		PTKc_Btk_Bmx	431..686	CDD:173657
		Pkinase_Tyr	436..685	CDD:285015
skb5	NP_588016.1	SH3_Nbp2-like	84..138	CDD:212799	20/53 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000