Protein Alignment Atp8a2 and CG33298

DIOPT Version :10

• Sequence 1: XP_038949921.1
• Gene: Atp8a2 / 691889
• RGDID: 1594597
• Length: 1200
• Species: Rattus norvegicus
• Sequence 2: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Alignment Length: 1304
• Identity: 418/1304 - (32%)
• Similarity: 634/1304 - (48%)
• Gaps: 250/1304 - (19%)

  Rat    46 SVGDQLEAPA-RIIYLN---------QSHLN-KFCDNRISTAKYSVLTFLPRFLYEQIRRAANAF 99
            :.||:.|..: |.:..|         :.|.| :|..|:|.|.||::|:|:|:.|.||..|.||.:
  Fly   217 NTGDKFEERSYRTVVPNHTVPPKTPKRDHPNGQFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLY 281

  Rat   100 FLFIALLQQIPDVSPTGRYTTLVPLVIILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNG---M 161
            |:||.||..:|::|..|:...::|::.:|.:..:|::.||.:|..:|..:| ..|..:.:|   .
  Fly   282 FIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRIN-NTTCRVYDGETER 345

  Rat   162 WHTIMWKEVAVGDIVKVLNGQYLPADMVLFSSSEPQGMCYVETANLDGETNLKIRQGLSHTADMQ 226
            :..:.|:|:.|||||.:.|.:.:|||::|..:|:|||:||::|.:||||||||.|:.:....:||
  Fly   346 YKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQ 410

  Rat   227 TREVLMKLSGRIECEGPNRHLYDFTGTL-HLDGKSSVALGPDQILLRGTQLRNTQWVFGVVVYTG 290
            :..|..|...|:|.:.|...||.|.|.| |..|: .|.:..:.:|||.::|:||.::.|:|||.|
  Fly   411 SIFVPSKFVSRVEADAPTTKLYRFHGALIHPTGE-RVPISTECLLLRESRLKNTDYIEGIVVYAG 474

  Rat   291 HDTKLMQNSTKAPLKRSNVEKVTNVQILVLFGILLVMALVSSVGALFWNGS--HGGKSWYIKKMD 353
            |:||.|.|::....|||.||:..|:.::....|||::.:|.::|...|..|  |....:......
  Fly   475 HETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMWLSSFTHFPVPYLPPNKL 539

  Rat   354 TTSDNFGYNLLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMYYIENDTPAMARTSNLNEE 418
            |.:....:...|:|::...:||:||.||:|:.|..|...|:.:.|::..|.:.....|..|:.||
  Fly   540 TANMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEE 604

  Rat   419 LGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGHFP-ELAREQSSDDFCRMTSCPSDSCDFNDPR 482
            |||::::|:|||||||.|.|.|::|.:.|..|.|.| ||.:..|..........|:|:.: :|..
  Fly   605 LGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPPSELEKIYSKPGAPAPPLIPNDNLN-SDMA 668

  Rat   483 LLKNIEDEHPTAPCIQEFLTLLAVCHTVV----PEKD---------------------------- 515
            .|.......|.|..|||||.:||:|:||:    |.:|
  Fly   669 QLTQGTYLTPHAQRIQEFLVVLAICNTVIVGAAPHRDMMNASGIIEVQQIGNSPANLKHGKQRQK 733

  Rat   516 ----------------------------GDEIIYQASSPGV------------------------ 528
                                        .|..|..|.|..|
  Fly   734 LLASSTSTTTTTTIINGPTTQPQVVSIPADRYIRLAESRSVTPSPPPNLLFALPAQSHQPTLSPI 798

  Rat   529 ----------------------------------------NLCGVGSLL---------------- 537
                                                    .:..:.:.|
  Fly   799 SSSAESSPNSESESPSPPMKNKSLSNSISPTGRAKAVINSKITSIATFLNAKTQGKRMKLPSSKT 863

  Rat   538 -----------------ADEAALVKGAKKLGFVFTGRTPYSVIIE--AMGQEQTFGILNVLEFSS 583
                             .||.|||..|.........|:|..:::.  ..|..:.:.||.||.|.|
  Fly   864 GTIYRTADGRPLYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDS 928

  Rat   584 DRKRMSVIVR-MPSGQLRLYCKGADNVIFERL------SKDSKYMEETLCHLEYFATEGLRTLCV 641
            .||.||::|| :.|.::.||.||||:.|...|      |.:....|:|...|:.:|.||||.|.:
  Fly   929 SRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVM 993

  Rat   642 AYADLSENEYEEWLKVYQEASIILKDRAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATL 706
            |...|:..:|.:|...:||..:.|::|.:||.:.:..:|.||.|||||.||||||.|||||||:|
  Fly   994 AKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASL 1058

  Rat   707 LKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDATRAAITQHCTDLGN-----LL 766
            |.|.|.:|||||||.||||||.||.:|.:|.|.||.|...|.||...||..:.||:.|     .|
  Fly  1059 LSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDMENDKTTSTL 1123

  Rat   767 G-----KENDVALIIDGHTLKYAL--SFEVRRSFLDLALSCKAVICCRVSPLQKSEIVDVVKKRV 824
            |     ::...||::||.||.:.|  ..::...||.|:..|.:|:|||.:||||:.:|.|||:.:
  Fly  1124 GYGQSLRKKQRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEEL 1188

  Rat   825 KAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTK 889
            ...|||||||||||.|||.|.|||||||.|||||...:|:.:.:|.|||:|||.||.|.|:|:::
  Fly  1189 NLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSR 1253

  Rat   890 CILYCFYKNVVLYIIELWFAFVNGFSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLR 954
            .|||.||||.....:..|:....|||||::.::..:.|||:|||:|||..:|::::...::.:|:
  Fly  1254 MILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLK 1318

  Rat   955 FPQLYKITQNAEGFNTKVFWGHCINALVHSLILFWVPMKA-LEHDTPLTSGHATDYLFVGNIVYT 1018
            .|.|||..:....:....||...::||..||::|:|.:.| .|.|             ||...:.
  Fly  1319 NPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESD-------------VGIWEFG 1370

  Rat  1019 YVVVTVCLKAGL-----ETTAWTKFSHLAV---WGSMLIWLVF--------FGVYSTFWPTIPIA 1067
            ..:...||.|.|     |..:||....|::   .||..::.:.        |||.|::|...
  Fly  1371 TTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSFYLFAIVYDSVCMNCFGVRSSYWVIF--- 1432

  Rat  1068 PDMKGQATMVLSSAHFWLGLLL-----VPTACLIEDVAWRAAKHTCKKTLLEEVQELETKSRVMG 1127
                    :..:||..||.::|     |....|:..|..........|.:|:..:|     |..|
  Fly  1433 --------VCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCPDDSTKVILQSKRE-----RSRG 1484

  Rat  1128 KAML 1131
            :|:|
  Fly  1485 EALL 1488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atp8a2	XP_038949921.1	ATPase-Plipid	68..1118	CDD:273734	406/1256 (32%)
CG33298	NP_995666.1	P-type_ATPase_APLT_Dnf-like	252..1355	CDD:319770	374/1105 (34%)