DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spata5l1 and TER94

DIOPT Version :9

Sequence 1:	NP_001103117.1	Gene:	Spata5l1 / 691729	RGDID:	1595990	Length:	747	Species:	Rattus norvegicus
Sequence 2:	NP_001097249.1	Gene:	TER94 / 36040	FlyBaseID:	FBgn0286784	Length:	826	Species:	Drosophila melanogaster

Alignment Length:	694	Identity:	235/694 - (33%)
Similarity:	374/694 - (53%)	Gaps:	85/694 - (12%)

- Green bases have known domain annotations that are detailed below.

  Rat    99 SCPPL---RRLEVWPVLRPQAGAPSSDAVLEVSQE---LLRNRPVSRGHVVATPPGIPGPVAALH 157
            |||.:   :|:.:.|:.....|...:  :.|:..:   |...||:..|........: .|:....
  Fly   126 SCPDVKYGKRVRILPIDESTEGVTGN--LFEIYLKPYFLEAYRPIHMGDNFIVRAAM-RPIEFKV 187

  Rat   158 VVSGTPDPEPAGRVTPHTRITLSDKPPPQVEPP------GEVTLGGLSETADSLRELLRLPLCYP 216
            |::   ||||...|.|.|.|.....|..:.|..      |...:||..:....::|::.|||.:|
  Fly   188 VLT---DPEPYCIVAPETVIFCDGDPIKREEEEESLNAVGYDDIGGCRKQLAQIKEMVELPLRHP 249

  Rat   217 LALAALGLAVPRGVLLAGPPGVGKTQLVRAVAREAGAELLAVSAPALQGTRPGETEENVRRVFQR 281
            ....|:|:..|||:|:.||||.|||.:.||||.|.||....::.|.:.....||:|.|:|:.|:.
  Fly   250 SLFKAIGVKPPRGILMYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEE 314

  Rat   282 AQELASRGPSLLFLDEVDALCPRRGGPQRAPESRVVAQVLTLLDGIHGDREVVVVGATNRPDELD 346
            |::   ..|:::|:||:||:.|:|.......|.|:|:|:|||:||:.....::|:.|||||:.:|
  Fly   315 AEK---NSPAIIFIDEIDAIAPKRDKTHGEVERRIVSQLLTLMDGMKKSSHLIVMAATNRPNSID 376

  Rat   347 PALRRPGRFDREVIIGTPTLKQREAILGVITSKMPISSHIDLGLLAEMTVGYVGADLTALCREAA 411
            |||||.||||||:.||.|....|..:|.:.|..|.:...:||..:|..:.|:|||||.:||.|||
  Fly   377 PALRRFGRFDREIDIGIPDATGRLEVLRIHTKNMKLHDDVDLEQIAAESHGHVGADLASLCSEAA 441

  Rat   412 TCALLKNEK----NQNNPKIEE----------TDFLEAFKKVQPSSFRSSIGLTDIRPVGWEQIG 462
            ...:  .||    :..:.||:.          .:|..|..|..||:.|.::  .::....|..||
  Fly   442 LQQI--REKMDLIDLEDDKIDAEVLASLAVTMENFRYAMTKSSPSALRETV--VEVPNTTWTDIG 502

  Rat   463 GLEDVKLKLKQCVEWPLKFPQEFARMGLTQPKGLLLYGPPGCAKTTLVRALATSCHCSFVSVCGA 527
            |||.||.:|::.|::|::.|.:|.:.|:...:|:|.||||||.||.|.:|:|..|..:|:||.|.
  Fly   503 GLESVKKELQELVQYPVEHPDKFLKFGMQPSRGVLFYGPPGCGKTLLAKAIANECQANFISVKGP 567

  Rat   528 DLFSPFVGDSEKVLSQVFRQARANTPALVFLDEIDSVLGSR--SVGSSGCDARERVLSVLLNELD 590
            :|.:.:.|:||..:..:|.:||:..|.::|.||:||:..:|  :||.:| .|.:||::.:|.|:|
  Fly   568 ELLTMWFGESEANVRDIFDKARSAAPCVLFFDELDSIAKARGGNVGDAG-GAADRVINQILTEMD 631

  Rat   591 GVGVRTVERRGSKASQQECQEILSRSVMIVVATNRPDVLDDALLRPGRLDKMVYVPPPDREGRLS 655
            |:|.:                   ::|.|:.||||||::|.|:|||||||:::|:|.||.:.|.:
  Fly   632 GMGAK-------------------KNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDDKSREA 677

  Rat   656 ILKVCTNNMPIGLNVSLENLAAETCYFSGADLRNLCKEAALFALQ--------------ENGLEA 706
            |||......|:...|.|..:|..|..||||||..:|:.|...|::              ||...|
  Fly   678 ILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKLAIRQAIEAEIRREKERAENQNSA 742

  Rat   707 TTVEQE---------HFTEALKTVKPSLTLKDLTFYENLFKKEL 741
            ..::::         ||.||:|..:.|::..|:..|| :|.:.|
  Fly   743 MDMDEDDPVPEITSAHFEEAMKFARRSVSDNDIRKYE-MFAQTL 785

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spata5l1	NP_001103117.1	CDC48	14..738	CDD:273521	233/689 (34%)
		AAA	230..362	CDD:278434	58/131 (44%)
		AAA	496..646	CDD:278434	60/151 (40%)
TER94	NP_001097249.1	CDC48	47..787	CDD:273521	235/694 (34%)
		CDC48_N	47..129	CDD:280513	2/2 (100%)
		CDC48_2	153..213	CDD:215011	16/63 (25%)
		AAA	263..392	CDD:278434	58/131 (44%)
		AAA	536..669	CDD:278434	60/152 (39%)
		Vps4_C	<741..783	CDD:286426	11/42 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D169540at33208
OrthoFinder	1	1.000	-	-		FOG0000137
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820