Protein Alignment TBXAS1 and Cyp9f2

DIOPT Version :9

• Sequence 1: NP_001159725.2
• Gene: TBXAS1 / 6916
• HGNCID: 11609
• Length: 579
• Species: Homo sapiens
• Sequence 2: NP_650189.1
• Gene: Cyp9f2 / 41520
• FlyBaseID: FBgn0038037
• Length: 516
• Species: Drosophila melanogaster
• Alignment Length: 592
• Identity: 151/592 - (25%)
• Similarity: 263/592 - (44%)
• Gaps: 119/592 - (20%)

Human    21 SVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLT--FFRQGFWESQMELRKLYGPLC----- 78
            ::|.....:|.|.:. ...:..|:.:.||..:.||:.  |.|:         |.::..:|
  Fly    10 AIAAALFYRWASANN-DFFKDRGIAYEKPVLYFGNMAGMFLRK---------RAMFDIVCDLYTK 64

Human    79 -------GYYLGRRMFIVISEPDMIKQVLVENFSNFTNR---MASGL-----EFKSVADSVLF-L 127
                   |.:..|:..:::.:||:|||:.:::|.:|.|.   .|:..     :..::..|.|| :
  Fly    65 GGSKKFFGIFEQRQPLLMVRDPDLIKQITIKDFDHFINHRNVFATSSDDDPHDMSNLFGSSLFSM 129

Human   128 RDKRWEEVRGALMSAFSPEKLNELGLLIMQERIKGHMGGQQAPQRIPPTRLSKPSGIYVNLHYAT 192
            ||.||:::|..|..||:..|:.::..|:.|
  Fly   130 RDARWKDMRSTLSPAFTGSKMRQMFQLMNQ----------------------------------- 159

Human   193 LPFCMVPLISQACDLLLAHLKRYAESGDAFDIQRCYC-NYTTDVVASVAFGTPVDSWQAPEDPFV 256
                   :..:|.|.|.....|..|  :..|: :.|| .:|.||:||.|||..|:|::..|:.|.
  Fly   160 -------VAKEAVDCLKQDDSRVQE--NELDM-KDYCTRFTNDVIASTAFGLQVNSFKDRENTFY 214

Human   257 KHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERR 321
            :..|:...|...:.:..:|..                  .|.| .||:::  :.|.|:::.:.
  Fly   215 QMGKKLTTFTFLQSMKFMLFF------------------ALKG-LNKILK--VELFDRKSTQY-- 256

Human   322 RDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLI 386
              |:::||||........:...|::..:..:.|.   ...:...:...|..:..:||.|.|:|..
  Fly   257 --FVRLVLDAMKYRQEHNIVRPDMINMLMEARGI---IQTEKTKASAVREWSDRDIVAQCFVFFF 316

Human   387 AGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKE----KHMAPEFCSLEEGLPYLDMVIAETL 447
            ||:|.....:.|..:.|..|.|.|::|..||....:    |.:..|...   |:.|||.|:.|.|
  Fly   317 AGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKELTYEAIM---GMKYLDQVVNEVL 378

Human   448 RMYPPAFRFTREAAQDC--EVLGQRIPA--GAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQ 508
            |.:|.|....||..:|.  :|.||::..  |.|:.:.....|.||:::.:|..|:||||:.|.::
  Fly   379 RKWPAAIAVDRECNKDITFDVDGQKVEVKKGDVIWLPTCGFHRDPKYFENPMKFDPERFSDENKE 443

Human   509 QHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQL-ESKSALGPKNGV 572
            ..:||||.|||.|.|:|:|.|..|||.|..:.::|..:||....::.:||:| .|...|.||.|.
  Fly   444 SIQPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYRFAPAKKSCIPLELITSGFQLSPKGGF 508

Human   573 YIKIVSR 579
            :||:|.|
  Fly   509 WIKLVQR 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBXAS1	NP_001159725.2	p450	47..576	CDD:306555	144/561 (26%)
Cyp9f2	NP_650189.1	p450	36..510	CDD:278495	143/558 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	277	1.000	Inparanoid score	I2940
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm8623
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2429
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.900