Protein Alignment TBX6 and tbx-8

DIOPT Version :9

• Sequence 1: NP_004599.2
• Gene: TBX6 / 6911
• HGNCID: 11605
• Length: 436
• Species: Homo sapiens
• Sequence 2: NP_499287.2
• Gene: tbx-8 / 176450
• WormBaseID: WBGene00006545
• Length: 315
• Species: Caenorhabditis elegans
• Alignment Length: 350
• Identity: 109/350 - (31%)
• Similarity: 141/350 - (40%)
• Gaps: 83/350 - (23%)

Human    91 VSLSLENRELWKEFSSVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQG 155
            |:|..:..:||..|.....|||:||:||:|||.....|.||.|...|..:|.:.|.|..||::..
 Worm     7 VTLREDQDKLWNLFHYHKNEMIVTKSGRKMFPKLEYVVRGLTPNKLYAMMLHIEPSDDHRYKFSS 71

Human   156 RRWEPSGKAEP-RLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLI-LHSMHKY-- 216
            ..|..|||||. |.|.::: |.|...:|..||..||.|.|||:||.....:..:| |||||||
 Worm    72 GEWVKSGKAEKHREPKKLW-HADGVRSGKEWMTNPVCFDRVKITNCAESTNASMIFLHSMHKYTP 135

Human   217 ----------------QPRIHLVRAAQLCSQHWGGMASFRFPETTFISVTAYQNPQITQLKIAAN 265
                            ||...||             .|.|...|.||:||||||..:.:|||..|
 Worm   136 VMSIYESPSESPFSVPQPSTRLV-------------TSVRLTYTEFIAVTAYQNDAVIKLKIKFN 187

Human   266 PFAKGFRENGRNCKRERDARVKRKLRGPEPAATEAYGSGDTPGGPCDSTLGGDIRESDPEQAPAP 330
            |||||||| |....|:|::          |:|.::            :|.....:.|.|:  |..
 Worm   188 PFAKGFRE-GSQSDRKRNS----------PSADDS------------TTDESSSQVSSPQ--PKK 227

Human   331 GEATAAPAPLCGGPSAEAYLLHPAAFHGAPSHLPTRSPSFPEAPDSGRSAPYSAAFLELPHGSGG 395
            ....:...||                  .|..|||..|..|.......|.||      ..|.:..
 Worm   228 SRTVSVSPPL------------------MPRILPTMIPPPPAINPLFYSLPY------FSHLAAT 268

Human   396 SGYPAAPPAVPFAPHFLQGGPFPLP 420
            ..:|..|...||.........||.|
 Worm   269 GNFPPVPFQFPFGLPCFSPMSFPTP 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBX6	NP_004599.2	TBOX	90..277	CDD:238106	82/205 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	271..339		12/67 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	360..379		6/18 (33%)
tbx-8	NP_499287.2	TBOX	4..199	CDD:238106	82/206 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C161449135
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840