Protein Alignment TBX5 and tbx-9

DIOPT Version :9

• Sequence 1: XP_016875401.1
• Gene: TBX5 / 6910
• HGNCID: 11604
• Length: 534
• Species: Homo sapiens
• Sequence 2: NP_499286.2
• Gene: tbx-9 / 176449
• WormBaseID: WBGene00006546
• Length: 292
• Species: Caenorhabditis elegans
• Alignment Length: 308
• Identity: 101/308 - (32%)
• Similarity: 140/308 - (45%)
• Gaps: 45/308 - (14%)

Human    67 MEGIKVFLH--ERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 129
            |..:||.:.  :..||..||....|||:||.||::||..:..|.||:....|.:::.:.|..:.|
 Worm     1 MSKVKVSIEGSQETLWKIFHAEVNEMIVTKNGRKLFPKLEYIVEGLDENKLYAIMLQLQPVGESR 65

Human   130 YKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTN-NHLDPFGHIILNSMH 193
            :||:..||..|||||..:..:...|.|....|:.||...:.|.::|::| :..:....|.|||||
 Worm    66 FKFSGGKWQETGKAEKQVDAKKMWHADGVRKGSDWMWSSICFDRVKISNYSESNNASMIYLNSMH 130

Human   194 KYQPRLHIVKADENNGF---GSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGS 255
            ||.|.|.|.::...:.|   .|.|....|..||.|.|||||:|||.|||.|||::|.||||||
 Worm   131 KYIPVLTIYESPSESPFCVPQSSNQIVATAKFPHTEFIAVTAYQNQKITDLKIKHNSFAKGFR-- 193

Human   256 DDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGPSQDL 320
             |..|.|..|..|            ....||....|.:||:....:.|.|
 Worm   194 -DGNLSRKRRSPS------------YSDGSNSQSPSPKSRSPPEVAPLQS--------------- 230

Human   321 LPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEEDS 368
            :||.||:.....|..         .|......|:..|::...||...|
 Worm   231 MPPINPFLFYFPHML---------SENLPVQFPFAFPFLSPLPSTPSS 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBX5	XP_016875401.1	TBOX	69..257	CDD:238106	77/193 (40%)
tbx-9	NP_499286.2	TBOX	3..198	CDD:238106	78/197 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C161449212
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	115	1.000	Inparanoid score	I3812
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.890