Protein Alignment TBX2 and ocm

DIOPT Version :10

• Sequence 1: NP_005985.3
• Gene: TBX2 / 6909
• HGNCID: 11597
• Length: 712
• Species: Homo sapiens
• Sequence 2: NP_611894.1
• Gene: ocm / 37874
• FlyBaseID: FBgn0266083
• Length: 2175
• Species: Drosophila melanogaster
• Alignment Length: 186
• Identity: 35/186 - (18%)
• Similarity: 66/186 - (35%)
• Gaps: 42/186 - (22%)

Human    10 LQARTQDEEKQASALQRIQVVHSFDIFQMLDMLQDLRGTMAQQATASSGTVKVVIV----DSVTA 70
            :|..|..|..:.....:|.|    |...::.:::.     ........|.:.:|:.    |::|.
  Fly   127 IQLTTDKEHLEKGTKDKIYV----DYVNIVKVVKP-----GDHVFVDDGLISLVVESISGDTLTC 182

Human    71 VV--APLLGGQQREGLALMMQLARELKILARDLGVAVVVTNHLTRDRDSRRFKPALGRS---WSF 130
            .|  ..:||  .|:|:.|.              ||.|.:.....:|:....|....|..   .||
  Fly   183 TVENGGMLG--SRKGVNLP--------------GVPVDLPAVSEKDKSDLAFGVEQGVDVIFASF 231

Human   131 VPSTRILLEVFEGAGTLGRSQRTVRLIKSPRQPTGLQEVIDI--------GTLGTE 178
            :.:...|.|:....|..|:..:.:..|::.:....|.::|:.        |.||.|
  Fly   232 IRNAAALKEIRTILGEKGKHIKIISKIENQQGMQNLDKIIEATDGIMVARGDLGIE 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBX2	NP_005985.3	T-box_TBX2_3-like	103..287	CDD:410314	18/87 (21%)
		PHA03307	300..>467	CDD:223039
		TBX	305..383	CDD:432659
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	313..450
		Repression domain 1 (RD1). /evidence=ECO:0000269|PubMed:11062467, ECO:0000269|PubMed:30599067	518..601
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	637..687
ocm	NP_611894.1	MGA_dom	771..821	CDD:464998
		PRK12323	<1933..>2053	CDD:481241