Protein Alignment TBP and tbp

DIOPT Version :10

• Sequence 1: NP_003185.1
• Gene: TBP / 6908
• HGNCID: 11588
• Length: 339
• Species: Homo sapiens
• Sequence 2: NP_956390.1
• Gene: tbp / 368882
• ZFINID: ZDB-GENE-030616-563
• Length: 302
• Species: Danio rerio
• Alignment Length: 341
• Identity: 273/341 - (80%)
• Similarity: 283/341 - (82%)
• Gaps: 41/341 - (12%)

Human     1 MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQ 65
            |:|||||||:||||||||||||||:|||||||||||||||||:||:||||:||||||||||||..
Zfish     1 MEQNNSLPPFAQGLASPQGAMTPGLPIFSPMMPYGTGLTPQPVQNSNSLSLLEEQQRQQQQQQAA 65

Human    66 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHS--QTLT 128
            .||                                       |....|.|||.|||:||  ...|
Zfish    66 SQQ---------------------------------------QGGMVGGSGQTPQLYHSTQAVST 91

Human   129 TAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYN 193
            |..|||.||||.:|:||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish    92 TTALPGNTPLYTTPLTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYN 156

Human   194 PKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNM 258
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   157 PKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNM 221

Human   259 VGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYE 323
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.||||
Zfish   222 VGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRGEIYE 286

Human   324 AFENIYPILKGFRKTT 339
            |||||||||||||||:
Zfish   287 AFENIYPILKGFRKTS 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBP	NP_003185.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21		17/19 (89%)
		polyglutamine repeat	58..95		8/36 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	127..159		24/31 (77%)
		PLN00062	162..338	CDD:177693	174/175 (99%)
		Repetitive region	165..241		75/75 (100%)
		Repetitive region	255..332		75/76 (99%)
tbp	NP_956390.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		18/20 (90%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	50..81		20/69 (29%)
		PLN00062	125..301	CDD:177693	174/175 (99%)
		1. /evidence=ECO:0000255	128..204		75/75 (100%)
		2. /evidence=ECO:0000255	218..295		75/76 (99%)