Protein Alignment TBP and tbp1

DIOPT Version :10

• Sequence 1: NP_003185.1
• Gene: TBP / 6908
• HGNCID: 11588
• Length: 339
• Species: Homo sapiens
• Sequence 2: NP_594566.1
• Gene: tbp1 / 2541582
• PomBaseID: SPAC29E6.08
• Length: 231
• Species: Schizosaccharomyces pombe
• Alignment Length: 227
• Identity: 154/227 - (67%)
• Similarity: 180/227 - (79%)
• Gaps: 7/227 - (3%)

Human   114 TSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASES---SGIVPQLQNIVSTVNLG 175
            |:.||....::.:||...||...    :..|..|..:.....|::   |||||.|||||:||||.
pombe     8 TASQASAFMNNSSLTFPVLPNAN----NEATNETADSGDAEVSKNEGVSGIVPTLQNIVATVNLD 68

Human   176 CKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARV 240
            |:||||||||.|||||||||||||||||||||::|||||:|||||..|.|||:.|:||:|||||:
pombe    69 CRLDLKTIALHARNAEYNPKRFAAVIMRIREPKSTALIFASGKMVVLGGKSEDDSKLASRKYARI 133

Human   241 VQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIF 305
            :|||||.|||.||||||:|||||||||||||||..:|..||||||||||||||||:||::|||||
pombe   134 IQKLGFNAKFTDFKIQNIVGSCDVKFPIRLEGLAYSHGTFSSYEPELFPGLIYRMVKPKVVLLIF 198

Human   306 VSGKVVLTGAKVRAEIYEAFENIYPILKGFRK 337
            ||||:||||||||.|||:|||.|||:|..|||
pombe   199 VSGKIVLTGAKVREEIYQAFEAIYPVLSEFRK 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBP	NP_003185.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		polyglutamine repeat	58..95
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	127..159		7/34 (21%)
		PLN00062	162..338	CDD:177693	141/176 (80%)
		Repetitive region	165..241		61/75 (81%)
		Repetitive region	255..332		63/76 (83%)
tbp1	NP_594566.1	PLN00062	55..230	CDD:177693	139/174 (80%)