Protein Alignment TBCE and Tbce

DIOPT Version :10

• Sequence 1: NP_001274730.1
• Gene: TBCE / 6905
• HGNCID: 11582
• Length: 578
• Species: Homo sapiens
• Sequence 2: NP_848027.1
• Gene: Tbce / 70430
• MGIID: 1917680
• Length: 524
• Species: Mus musculus
• Alignment Length: 579
• Identity: 392/579 - (67%)
• Similarity: 449/579 - (77%)
• Gaps: 56/579 - (9%)

Human     1 MSDTLTADVIGRRVEVNGEHATVRFAGVVPPVAGPWLGVEWDNPERGKHDGSHEGTVYFKCRHPT 65
            |||.|..||||||||||||:|||||.|.||||||.|||||||||||||||||||||:||||||||
Mouse     1 MSDILPLDVIGRRVEVNGEYATVRFCGAVPPVAGLWLGVEWDNPERGKHDGSHEGTMYFKCRHPT 65

Human    66 GGSFIRPNKVNFGTDFLTAIKNRYVLEDGPEEDRKEQIVTIGNKPVETIGFDSIMKQQSQLSKLQ 130
            ||||:||:|||||.|||||:|.||||||||::|.....:.:|:|.|:||||:.|.|:||||..||
Mouse    66 GGSFVRPSKVNFGDDFLTALKKRYVLEDGPDDDENSCSLKVGSKQVQTIGFEHITKKQSQLRALQ 130

Human   131 EVSLRNCAVSCAGEKGGVAEACPNIRKVDLSKNLLSSWDEVIHIADQLRHLEVLNVSENKLKFPS 195
            ::||.|||||.|||:|.:||||||||.|:|||||||:||||:.||:||:.||.|::|||||:|||
Mouse   131 DISLWNCAVSHAGEQGRIAEACPNIRVVNLSKNLLSTWDEVVLIAEQLKDLEALDLSENKLQFPS 195

Human   196 GS-VLTGTLSVLKVLVLNQTGITWAEAHAQCGGSRHGLDMQKDASKFVDLCVLQKCSTSNCIISA 259
            .| .||.|.|.||.||||:|||||.|
Mouse   196 DSPTLTRTFSTLKTLVLNKTGITWTE--------------------------------------- 221

Human   260 KDHTSMRMNVAKVLRCVAGCPGLEELYLESNNIFISERPTDVLQTVKLLDLSSNQLIDENQLYLI 324
                        ||.|....|.||||||:||||.|||||.:|||.::|||||||..|||:||.||
Mouse   222 ------------VLHCAPSWPVLEELYLKSNNISISERPVNVLQKMRLLDLSSNPSIDESQLSLI 274

Human   325 AHLPRLEQLILSDTGISSLHFPDAGIGCKTSMFPSLKYLVVNDNQISQWSFFNELEKLPSLRALS 389
            |.|||||.|:|||.|:||:|||||.|||||||||:||||:|||||||:|||.|||:||.||:|||
Mouse   275 ADLPRLEHLVLSDIGLSSIHFPDAEIGCKTSMFPALKYLIVNDNQISEWSFINELDKLQSLQALS 339

Human   390 CLRNPLTKEDKEAETARLLIIASIGQLKTLNKCEILPEERRRAELDYRKAFGNEWKQAGGHKDPE 454
            |.||||:|.||..|    :|||.|.||:|||:|:|||||||.|||||||||||||::||||.||:
Mouse   340 CTRNPLSKADKAEE----IIIAKIAQLRTLNRCQILPEERRGAELDYRKAFGNEWRKAGGHPDPD 400

Human   455 KNRLSEEFLTAHPRYQFLCLKYGAPEDWELKTQQPLMLKNQLLTLKIKYPHQLDQKVLEKQLPGS 519
            |||.:..||:||||||.||.|||||||.|||||||.|||.||||||||..:|.::::||||||.|
Mouse   401 KNRPNAAFLSAHPRYQLLCCKYGAPEDEELKTQQPFMLKKQLLTLKIKCSNQPERQILEKQLPDS 465

Human   520 MTIQKVKGLLSRLLKVPVSDLLLSYESPKKPGREIELENDLKSLQFYSVENGDCLLVRW 578
            ||:||||||||||||||||:|||||||.|.|||||||||||:.||||||||||||||||
Mouse   466 MTVQKVKGLLSRLLKVPVSELLLSYESSKMPGREIELENDLQPLQFYSVENGDCLLVRW 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBCE	NP_001274730.1	CAP_GLY	10..75	CDD:460154	57/64 (89%)
		LRR	113..>396	CDD:443914	166/283 (59%)
		leucine-rich repeat	129..154	CDD:275380	17/24 (71%)
		leucine-rich repeat	155..180	CDD:275380	18/24 (75%)
		leucine-rich repeat	181..205	CDD:275380	15/24 (63%)
		leucine-rich repeat	206..281	CDD:275380	15/74 (20%)
		Ribosomal_S21e	234..>272	CDD:460133	0/37 (0%)
		leucine-rich repeat	282..304	CDD:275380	17/21 (81%)
		leucine-rich repeat	305..329	CDD:275380	16/23 (70%)
		leucine-rich repeat	330..359	CDD:275380	22/28 (79%)
		leucine-rich repeat	385..415	CDD:275380	17/29 (59%)
		Ubl_TBCE	495..577	CDD:340564	66/81 (81%)
Tbce	NP_848027.1	CAP_GLY	10..75	CDD:214997	57/64 (89%)
		leucine-rich repeat	129..154	CDD:275380	17/24 (71%)
		LRR	<150..>346	CDD:443914	142/246 (58%)
		LRR 1	154..175		15/20 (75%)
		leucine-rich repeat	155..180	CDD:275380	18/24 (75%)
		LRR 2	180..201		12/20 (60%)
		leucine-rich repeat	181..206	CDD:275380	15/24 (63%)
		LRR 3	206..227		15/71 (21%)
		leucine-rich repeat	207..228	CDD:275380	15/71 (21%)
		LRR 4	231..253		16/21 (76%)
		leucine-rich repeat	232..254	CDD:275380	17/21 (81%)
		LRR 5	254..275		13/20 (65%)
		leucine-rich repeat	255..279	CDD:275380	16/23 (70%)
		LRR 6	279..300		15/20 (75%)
		leucine-rich repeat	280..309	CDD:275380	22/28 (79%)
		LRR 7	309..330		16/20 (80%)
		Ubl_TBCE	441..523	CDD:340564	66/81 (81%)