Protein Alignment TBCE and Tbce

DIOPT Version :10

• Sequence 1: NP_001274730.1
• Gene: TBCE / 6905
• HGNCID: 11582
• Length: 578
• Species: Homo sapiens
• Sequence 2: XP_063132689.1
• Gene: Tbce / 361255
• RGDID: 1305533
• Length: 564
• Species: Rattus norvegicus
• Alignment Length: 549
• Identity: 369/549 - (67%)
• Similarity: 420/549 - (76%)
• Gaps: 56/549 - (10%)

Human     1 MSDTLTADVIGRRVEVNGEHATVRFAGVVPPVAGPWLGVEWDNPERGKHDGSHEGTVYFKCRHPT 65
            |||.|..||||||||||||:|||||.|.||||||.|||||||||||||||||||||:||||||||
  Rat    30 MSDILPLDVIGRRVEVNGEYATVRFCGAVPPVAGLWLGVEWDNPERGKHDGSHEGTMYFKCRHPT 94

Human    66 GGSFIRPNKVNFGTDFLTAIKNRYVLEDGPEEDRKEQIVTIGNKPVETIGFDSIMKQQSQLSKLQ 130
            ||||:|||.||||.|||||:|.||||.|||::|.|...:.:|:|.|:||||:.|.|:||||..||
  Rat    95 GGSFVRPNIVNFGEDFLTALKKRYVLTDGPDDDEKSCSLKVGSKQVQTIGFEHITKKQSQLRSLQ 159

Human   131 EVSLRNCAVSCAGEKGGVAEACPNIRKVDLSKNLLSSWDEVIHIADQLRHLEVLNVSENKLKFPS 195
            ::||..||||||||:|.:||||||||.|||||||||:|||||.||:||:.||.|::|||||:|||
  Rat   160 DISLWKCAVSCAGERGRIAEACPNIRVVDLSKNLLSTWDEVILIAEQLKDLEALDLSENKLQFPS 224

Human   196 GS-VLTGTLSVLKVLVLNQTGITWAEAHAQCGGSRHGLDMQKDASKFVDLCVLQKCSTSNCIISA 259
            .| .||.|.|.||.||||:|||||.|
  Rat   225 DSPTLTRTFSTLKTLVLNKTGITWTE--------------------------------------- 250

Human   260 KDHTSMRMNVAKVLRCVAGCPGLEELYLESNNIFISERPTDVLQTVKLLDLSSNQLIDENQLYLI 324
                        ||.|....|.|:||||:||.|.|||||.:.||.::|||||||..|||:||.||
  Rat   251 ------------VLHCAPSWPVLQELYLKSNGISISERPVNALQNLRLLDLSSNPSIDESQLCLI 303

Human   325 AHLPRLEQLILSDTGISSLHFPDAGIGCKTSMFPSLKYLVVNDNQISQWSFFNELEKLPSLRALS 389
            |:|||||.|:|||.|:||:|||||.|||||||||:|.||:|||||||:|||.|||:||.||:|||
  Rat   304 AYLPRLEHLLLSDIGLSSIHFPDAEIGCKTSMFPALTYLIVNDNQISEWSFINELDKLQSLQALS 368

Human   390 CLRNPLTKEDKEAETARLLIIASIGQLKTLNKCEILPEERRRAELDYRKAFGNEWKQAGGHKDPE 454
            |.||||||.||..|    :|||.||||||||:|:|||||||.||||||||||.||::||||.||:
  Rat   369 CARNPLTKGDKAEE----IIIAKIGQLKTLNRCQILPEERRGAELDYRKAFGKEWRKAGGHPDPD 429

Human   455 KNRLSEEFLTAHPRYQFLCLKYGAPEDWELKTQQPLMLKNQLLTLKIKYPHQLDQKVLEKQLPGS 519
            :||.|.|||:||||||.||.|||||||.|||||||.||||||||||||..:|.:|::||||||.|
  Rat   430 RNRPSAEFLSAHPRYQLLCCKYGAPEDEELKTQQPFMLKNQLLTLKIKCSNQPEQQILEKQLPDS 494

Human   520 MTIQKVKGLLSRLLKVPVSDLLLSYESPK 548
            |||||||||||||||||||:|||||||.|
  Rat   495 MTIQKVKGLLSRLLKVPVSELLLSYESSK 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBCE	NP_001274730.1	CAP_GLY	10..75	CDD:460154	58/64 (91%)
		LRR	113..>396	CDD:443914	164/283 (58%)
		leucine-rich repeat	129..154	CDD:275380	17/24 (71%)
		leucine-rich repeat	155..180	CDD:275380	20/24 (83%)
		leucine-rich repeat	181..205	CDD:275380	15/24 (63%)
		leucine-rich repeat	206..281	CDD:275380	15/74 (20%)
		Ribosomal_S21e	234..>272	CDD:460133	0/37 (0%)
		leucine-rich repeat	282..304	CDD:275380	14/21 (67%)
		leucine-rich repeat	305..329	CDD:275380	16/23 (70%)
		leucine-rich repeat	330..359	CDD:275380	22/28 (79%)
		leucine-rich repeat	385..415	CDD:275380	18/29 (62%)
		Ubl_TBCE	495..577	CDD:340564	44/54 (81%)
Tbce	XP_063132689.1	None