Protein Alignment TAFAZZIN and TAZ1

DIOPT Version :10

• Sequence 1: NP_001427785.1
• Gene: TAFAZZIN / 6901
• HGNCID: 11577
• Length: 310
• Species: Homo sapiens
• Sequence 2: NP_015466.1
• Gene: TAZ1 / 856262
• SGDID: S000006344
• Length: 381
• Species: Saccharomyces cerevisiae
• Alignment Length: 285
• Identity: 77/285 - (27%)
• Similarity: 117/285 - (41%)
• Gaps: 85/285 - (29%)

Human    73 EKRGPATPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCV 137
            |.||    |:||.||.|.:|||.:|..|..:...:|..:||:..|.:|||..:..::|||||:
Yeast    67 ENRG----LMTVMNHMSMVDDPLVWATLPYKLFTSLDNIRWSLGAHNICFQNKFLANFFSLGQ-- 125

Human   138 PVCRGAEFFQAENEGKGVLDTGRHMPGAGKRREKGDGVYQKGMDFILEKLNHGD----------- 191
                             ||.|.|.          |.|.:|..:|..:..|:..|
Yeast   126 -----------------VLSTERF----------GVGPFQGSIDASIRLLSPDDTLDLEWTPHSE 163

Human   192 -------------------WVHIFPEGKV-----NMSSEFLRFKWGIGRLIAECHLNPIILPLWH 232
                               |||::|||.|     ...:....|||||.|:|.|....||::|::.
Yeast   164 VSSSLKKAYSPPIIRSKPSWVHVYPEGFVLQLYPPFENSMRYFKWGITRMILEATKPPIVVPIFA 228

Human   233 VGMNDVLPNS------PPYFPR-FGQKITVLIGKPFSALPVLERLRAENKSAVEM------RKAL 284
            .|...:...:      ....|| ||.:|.|.||.|.:. .:::|.|.|....||.      ...|
Yeast   229 TGFEKIASEAVTDSMFRQILPRNFGSEINVTIGDPLND-DLIDRYRKEWTHLVEKYYDPKNPNDL 292

Human   285 TDFIQ--EEFQHLKTQ-AEQLHNHL 306
            :|.::  :|.|.|::: |.:|..|:
Yeast   293 SDELKYGKEAQDLRSRLAAELRAHV 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TAFAZZIN	NP_001427785.1	None
TAZ1	NP_015466.1	LPLAT_AGPAT-like	41..282	CDD:153251	68/248 (27%)