Protein Alignment TAFAZZIN and acl-3

DIOPT Version :10

• Sequence 1: NP_001427785.1
• Gene: TAFAZZIN / 6901
• HGNCID: 11577
• Length: 310
• Species: Homo sapiens
• Sequence 2: NP_502202.2
• Gene: acl-3 / 178095
• WormBaseID: WBGene00006491
• Length: 284
• Species: Caenorhabditis elegans
• Alignment Length: 296
• Identity: 117/296 - (39%)
• Similarity: 157/296 - (53%)
• Gaps: 61/296 - (20%)

Human     7 WPFPAVPPLTWTLASSVVMGLVGTYSCFWTSEWAQAEAGPPGYPCPAGEYM-----NHLTVHNRE 66
            ||||..|.|.:.:.|.:.|.||.:.|                      :.|     |.|..||:|
 Worm    19 WPFPKKPSLLYRIKSYMTMSLVTSVS----------------------KLMFLGGSNKLICHNKE 61

Human    67 VLYELIEKRGPATPLITVSNHQSCMDDPHLWGILKLRHIWNLK-LMRWTPAAADICFTKELHSHF 130
            ...:::|  .|..||||||||:|.:|||.:|.|||.|..|..| ..|:|.||.:|||||:.|:..
 Worm    62 TFVKILE--NPNQPLITVSNHRSNIDDPLMWCILKFREFWRYKDRNRYTLAAHNICFTKQFHTTM 124

Human   131 FSLGKCVPVCRGAEFFQAENEGKGVLDTGRHMPGAGKRREKGDGVYQKGMDFILEKLNHGDWVHI 195
            ||||:|||..|                              |:|||||||||.::.||...||||
 Worm   125 FSLGRCVPCVR------------------------------GEGVYQKGMDFCVDMLNDNKWVHI 159

Human   196 FPEGKV-NMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIGK 259
            |||||| .:.||.||||||||||:.:...:|:|||:|...|..|.|..|||:|:||..:||.||:
 Worm   160 FPEGKVCTLESEPLRFKWGIGRLVMDAKTDPVILPVWCKEMEKVWPTQPPYYPKFGNTVTVHIGE 224

Human   260 PFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHL 295
            ||....:.:.:.:::.:..:|||.:||.:|.....|
 Worm   225 PFFLSDLKKTVLSKSLTTEQMRKIITDEVQTRMYQL 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TAFAZZIN	NP_001427785.1	None
acl-3	NP_502202.2	Acyltransferase	54..198	CDD:366704	82/175 (47%)