Protein Alignment TBX1 and Doc2

DIOPT Version :9

• Sequence 1: XP_016884414.1
• Gene: TBX1 / 6899
• HGNCID: 11592
• Length: 545
• Species: Homo sapiens
• Sequence 2: NP_648282.1
• Gene: Doc2 / 39038
• FlyBaseID: FBgn0035956
• Length: 469
• Species: Drosophila melanogaster
• Alignment Length: 361
• Identity: 129/361 - (35%)
• Similarity: 195/361 - (54%)
• Gaps: 68/361 - (18%)

Human   159 GVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYA 223
            ||.:.|:...||.:|:|:|||||:||:||||||:.::.:.|::..::|.:|::.||:.|.||:
  Fly    55 GVEMTLQNDDLWKQFHQIGTEMIITKSGRRMFPSMRLSVSGLEDESNYCVLLEMVPIGDCRYK-- 117

Human   224 FHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQ 288
            |..|.|:.||.|:|.:|.|::.||||||.||.|..|.:.|:|:|||||.||::|||:|.|||:||
  Fly   118 FSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQAQPILFNKVKLTNNTLDNSGHIVLASMHKYQ 182

Human   289 PRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDW 353
            ||.||:..   .|..:......:.|||.||.|.|||||||.|||:|||.:||||||||:
  Fly   183 PRLHVIRT---ADLAQIPWAPQQAFVFAETEFVAVTAYQNDRITKLKIDNNPFAKGFRE------ 238

Human   354 PRNHRPGALPLMSAFARSRNPVASPTQPSGTEKDAAEARREFQRDAGGPAVLGDPAHPPQLLARV 418
                        :..:|.:..::|  .|:|.::|.:            |::    :|........
  Fly   239 ------------TGQSRCKRKMSS--SPTGEDQDQS------------PSL----SHSQSQSESD 273

Human   419 LSPSLPGAGGAGGLVPLPGAPGGRPSPPNPEL-RLEAPGASEPLHHHPYKYPAAAYDHYL--GAK 480
            :||:..|...|||...:..:.|       |:: ||.:.|::..|        :::.|...  ||.
  Fly   274 MSPTKGGGETAGGTSSIGDSDG-------PQIKRLRSNGSACSL--------SSSLDDQSVPGAS 323

Human   481 SRPAPYPLPGLRGHGYHPHAHPHHHHHPVSPAAAAA 516
            |.....|         .||.|.|.|.||:...:|::
  Fly   324 SLALGSP---------PPHLHSHSHPHPLQARSASS 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBX1	XP_016884414.1	None
Doc2	NP_648282.1	TBOX	55..242	CDD:238106	97/209 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.910