Protein Alignment TAL1 and Fer2

DIOPT Version :10

• Sequence 1: XP_047285001.1
• Gene: TAL1 / 6886
• HGNCID: 11556
• Length: 390
• Species: Homo sapiens
• Sequence 2: NP_001287359.1
• Gene: Fer2 / 41961
• FlyBaseID: FBgn0038402
• Length: 283
• Species: Drosophila melanogaster
• Alignment Length: 286
• Identity: 71/286 - (24%)
• Similarity: 94/286 - (32%)
• Gaps: 129/286 - (45%)

Human    55 GARGGPGGGPAGGGGAARDLKGRDAATAEARHRVPTTELCRPPGPAPAPAPASVTAELPGDGRMV 119
            ||.|| |||..||||::    |...::...||.                           ....:
  Fly    44 GATGG-GGGSGGGGGSS----GLRLSSNNLRHI---------------------------QQHYM 76

Human   120 QLSPPALAAPAAPGRALLYSLSQPLASLGRSG----------ARGQGPGAGRVGRATTPTGVSFY 174
            |.|          |..||.|.:.|:......|          |...|.|.|..|.||
  Fly    77 QHS----------GENLLDSSTNPMGVHNSGGGAPLMCNSPSASSSGGGCGNAGSAT-------- 123

Human   175 TSAAACPGGRAGGAQGEEVVLNPVALEPQAGAPDGFFGEPDAFPMFTTNNRVKRRPSPYEMEITD 239
                  |||                    ||.|:..:|...|           ...|.|:|:
  Fly   124 ------PGG--------------------AGGPNPGYGSVGA-----------ATASSYKMQ--- 148

Human   240 GPHTKVVRRIFTNSRERWRQQ----------NVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKY 294
                    |...|.|||.|.|          ::|.||.|||..:||.|.:|:|||.:.||||:.|
  Fly   149 --------RQAANVRERKRIQRSAPTGYTKCSINSAFDELRVHVPTFPYEKRLSKIDTLRLAIAY 205

Human   295 INFLAKLLNDQEEEGTQRAKTGKDPV 320
            |:.|.::|           :|..||:
  Fly   206 ISLLREVL-----------QTDYDPL 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TAL1	XP_047285001.1	bHLH_TS_TAL1	244..308	CDD:381549	28/73 (38%)
Fer2	NP_001287359.1	bHLH_SF	144..216	CDD:469605	30/93 (32%)