Protein Alignment TAL1 and sage

DIOPT Version :10

• Sequence 1: XP_047285001.1
• Gene: TAL1 / 6886
• HGNCID: 11556
• Length: 390
• Species: Homo sapiens
• Sequence 2: NP_524287.1
• Gene: sage / 41105
• FlyBaseID: FBgn0037672
• Length: 268
• Species: Drosophila melanogaster
• Alignment Length: 287
• Identity: 75/287 - (26%)
• Similarity: 105/287 - (36%)
• Gaps: 82/287 - (28%)

Human    96 PPGPAPAPAPASVTAELP-----GDGRMVQLSPPALAAPAAPGRALLYSLSQPLASLGRSGARGQ 155
            |..|.|...|.|.|...|     .:|.......|.|....||     .|.|.|..||..:..
  Fly    13 PGDPPPVLVPVSATTGGPYLSGGSEGEAESSEQPVLLELGAP-----QSSSCPAVSLNYTLT--- 69

Human   156 GPGAGRVGRATTPTGVSFYTSAAACPGGRAGGAQGE-----------EVVLNPVAL----EPQAG 205
            ..|||.:  |..||....|:.:.      .||.:.|           .|:..||::    :...|
  Fly    70 ADGAGLL--AYAPTHPHSYSPSV------MGGYEKEAHNMGLLPPTYSVIPQPVSMWHAGQVATG 126

Human   206 APDGF-FGEPDAF---PMF----------TTNNRVKRRPSP------YEMEITDGPHTKVVRRIF 250
            :|.|. ..:|...   ||:          :|...:.:..:|      .:||       |..||..
  Fly   127 SPVGLECNKPSELVPPPMYMSYSGGSIANSTEVDIAKEHNPAWREKALQME-------KDYRRTA 184

Human   251 TNSRERWRQQNVNGAFAELRKLIPTHPPD-KKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAK 314
            .: |||.|.:::|.||..||..:|...|: ||.||.|.||:|:.|||.|..:|.:..
  Fly   185 CD-RERTRMRDMNRAFDLLRSKLPISKPNGKKYSKIESLRIAINYINHLQAMLRESS-------- 240

Human   315 TGKDPVVGAGGGG---GGGGGGAPPDD 338
                  ||..|.|   ..||..:|.|:
  Fly   241 ------VGQNGNGCCAWSGGSSSPYDN 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TAL1	XP_047285001.1	bHLH_TS_TAL1	244..308	CDD:381549	27/64 (42%)
sage	NP_524287.1	bHLH_TS	181..236	CDD:381396	25/55 (45%)