Protein Alignment TAL1 and twi

DIOPT Version :10

• Sequence 1: XP_047285001.1
• Gene: TAL1 / 6886
• HGNCID: 11556
• Length: 390
• Species: Homo sapiens
• Sequence 2: NP_523816.2
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Alignment Length: 171
• Identity: 54/171 - (31%)
• Similarity: 77/171 - (45%)
• Gaps: 34/171 - (19%)

Human   195 LNPVALEPQAGAPDGFFGE--------PDAFPMFTTNNRVKRRPSPYEMEITDGPHTKVVRRIFT 251
            ||...:.|...|.||..|.        ..||.  ....|:||:||  :.|.||....   :|:..
  Fly   310 LNGGVMSPACLADDGSAGSLLDGSDAGGKAFR--KPRRRLKRKPS--KTEETDEFSN---QRVMA 367

Human   252 NSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQ--------EEE 308
            |.|||.|.|::|.||..|:::|||.|.| ||||.:.|:||.:||:||.::|:..        |.:
  Fly   368 NVRERQRTQSLNDAFKSLQQIIPTLPSD-KLSKIQTLKLATRYIDFLCRMLSSSDISLLKALEAQ 431

Human   309 GTQRAKTGKDPVVGAGGGG----------GGGGGGAPPDDL 339
            |:..|......::.|...|          ..|....||:.|
  Fly   432 GSPSAYGSASSLLSAAANGAEADLKCLRKANGAPIIPPEKL 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TAL1	XP_047285001.1	bHLH_TS_TAL1	244..308	CDD:381549	29/71 (41%)
twi	NP_523816.2	bHLH_TS_TWIST	363..421	CDD:381470	28/58 (48%)