Protein Alignment TAL1 and dimm

DIOPT Version :10

• Sequence 1: XP_047285001.1
• Gene: TAL1 / 6886
• HGNCID: 11556
• Length: 390
• Species: Homo sapiens
• Sequence 2: NP_523611.1
• Gene: dimm / 35404
• FlyBaseID: FBgn0023091
• Length: 390
• Species: Drosophila melanogaster
• Alignment Length: 383
• Identity: 84/383 - (21%)
• Similarity: 119/383 - (31%)
• Gaps: 162/383 - (42%)

Human    20 DAAEASMAPPHLVLLNGVAKETSRAAAAEPPVIELGARGGP--------GGGPAGGGGAARDLKG 76
            ::||.|..|        |.:.|.|.:.......:|......        |||.:.|||:
  Fly    40 ESAEGSSRP--------VRRATRRTSQLSNNTYDLEMTDSSSQSDDTSGGGGSSNGGGS------ 90

Human    77 RDAATAEARHRVPTTELCRPPGPAPAPAPASVTAELPGDGRMVQLSPPALAAPAAPGRALLYSLS 141
                         ||....|.|
  Fly    91 -------------TTNTGHPSG------------------------------------------- 99

Human   142 QPLASLGRSGARGQGP-GAGRVGRATTPTGVSFYTSAAACPGGRAGGAQGEEVVLNPVALEPQAG 205
               .|||     |||| |.|||.:|          |:.|||.           .:.|.:....:.
  Fly   100 ---CSLG-----GQGPSGRGRVQQA----------SSGACPS-----------TIAPNSTSSNSS 135

Human   206 APDGFFGEPDAFPMFTTNNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELR 270
            ..:|              |..:||......:      .:.:||:.:|.|||.|..::|.||..||
  Fly   136 NANG--------------NASRRRKGALNAK------ERNMRRLESNERERMRMHSLNDAFQSLR 180

Human   271 KLIPTHPPDKKLSKNEILRLAMKY-INFLAKLLNDQEEEGTQRAKTGKDPVVGAGGG-------- 326
            ::||....:::|||.|.|.||..| ||....:|:.:.||........     ||.||
  Fly   181 EVIPHVEMERRLSKIETLTLAKNYIINLTHIILSKRNEEAAALELNS-----GAVGGVLLSNLSS 240

Human   327 --GGGGGGGAPPDD-----LLQDVLSPNSS--C-------GSSLDGAASPDSYTEEPA 368
              ||....|.|.:.     ..:|.|:...:  |       ||.|:.|    :.|..||
  Fly   241 ESGGPVASGIPANSNAATICFEDTLASGGAFDCAILAATDGSLLNAA----TVTTSPA 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TAL1	XP_047285001.1	bHLH_TS_TAL1	244..308	CDD:381549	25/64 (39%)
dimm	NP_523611.1	bHLH_TS_dimmed_like	157..216	CDD:381555	25/58 (43%)