DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TAL1 and CG33557

DIOPT Version :9

Sequence 1:	NP_001274276.1	Gene:	TAL1 / 6886	HGNCID:	11556	Length:	331	Species:	Homo sapiens
Sequence 2:	NP_001014730.1	Gene:	CG33557 / 3346145	FlyBaseID:	FBgn0053557	Length:	150	Species:	Drosophila melanogaster

Alignment Length:	117	Identity:	42/117 - (35%)
Similarity:	59/117 - (50%)	Gaps:	19/117 - (16%)

- Green bases have known domain annotations that are detailed below.

Human   148 GSGFFGEPDAFPMFTTNNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRK 212
            |||...:.:       ::::.:..:|...| ..|.|.:...|...|:|||:|..|||.|:..||.
  Fly    30 GSGAAADSE-------DSQIGQEANPGGQE-NQGNHRRRPPRQKINARERYRTFNVNSAYEALRN 86

Human   213 LIPTHPPDKKLSKNEILRLAMKYINFLAK-----------LLNDQEEEGTQR 253
            ||||.|.::||||.||:|||..||..|:.           ||:..|.||..|
  Fly    87 LIPTEPMNRKLSKIEIIRLASSYITHLSSTLETGTECQPCLLHKYESEGITR 138

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TAL1	NP_001274276.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..27
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	40..86
		HLH	193..243	CDD:197674	28/60 (47%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	249..331		3/5 (60%)
CG33557	NP_001014730.1	HLH	67..119	CDD:197674	28/51 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810