Protein Alignment TAL1 and HLH3B

DIOPT Version :10

• Sequence 1: XP_047285001.1
• Gene: TAL1 / 6886
• HGNCID: 11556
• Length: 390
• Species: Homo sapiens
• Sequence 2: NP_525055.1
• Gene: HLH3B / 31249
• FlyBaseID: FBgn0011276
• Length: 376
• Species: Drosophila melanogaster
• Alignment Length: 378
• Identity: 101/378 - (26%)
• Similarity: 131/378 - (34%)
• Gaps: 171/378 - (45%)

Human    35 NGVAKETSRAAAAEPPVIELGARG------GPGGGPAGGGGAARDLKGRDAATAEARHRVPTTEL 93
            ||......|:.|:.      |:.|      .|..|...|.|:.||       ||..||   ...|
  Fly     9 NGADNADERSTASS------GSSGHSQTNESPRSGHLNGNGSMRD-------TAAGRH---PPAL 57

Human    94 CRPPGPAPAPAPASVTAELPGDG---------------------------------RMVQLSPPA 125
            .|...|...|...|::   .|||                                 |.:..||.:
  Fly    58 LRHATPHLQPKTESIS---DGDGDAELSDFSLNDTEEDEEDLRDYIVLNGNQADANRSLSSSPRS 119

Human   126 ------LAAPAAPGRALLYSLSQPLASLGRSGARGQGPGAGRVGRATTPTGVSFYTSAAACPGGR 184
                  |.|||:.|           :|:|.||. |.|.|:|  |.|:
  Fly   120 HSRNGLLTAPASSG-----------SSVGGSGG-GGGNGSG--GNAS------------------ 152

Human   185 AGGAQGEEVVLNPVALEPQAGAPDGFFGEPDAFPMFTTNNRVKRRPSPYEMEITDGPHTKVVRRI 249
            :||..|             .||..|                                    ||::
  Fly   153 SGGGSG-------------VGATGG------------------------------------VRKV 168

Human   250 FTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAK 314
            |||:|||||||||:|||||||||:||||||||||||||||.|:|||..|..:|..|:.:.
  Fly   169 FTNTRERWRQQNVSGAFAELRKLVPTHPPDKKLSKNEILRSAIKYIKLLTGILEWQQRQA----- 228

Human   315 TGKDPVVGAGGGGGGGGGGAPPDDLLQDVLSPNSSCGSSLDGAASPDSYTEEP 367
                                 |...::..:.||::.....:|.|:.....|.|
  Fly   229 ---------------------PSHPIRAQMEPNNNDNRMANGHAADGENLENP 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TAL1	XP_047285001.1	bHLH_TS_TAL1	244..308	CDD:381549	46/63 (73%)
HLH3B	NP_525055.1	bHLH_TS_dHLH3B_like	166..225	CDD:381551	44/58 (76%)