Protein Alignment TAL1 and ase

DIOPT Version :10

• Sequence 1: XP_047285001.1
• Gene: TAL1 / 6886
• HGNCID: 11556
• Length: 390
• Species: Homo sapiens
• Sequence 2: NP_476694.1
• Gene: ase / 30985
• FlyBaseID: FBgn0000137
• Length: 486
• Species: Drosophila melanogaster
• Alignment Length: 347
• Identity: 84/347 - (24%)
• Similarity: 117/347 - (33%)
• Gaps: 119/347 - (34%)

Human   100 APAPAPASVTAELPGDGRMVQLSPPALAAPAAPGRALLYSLSQPLASLGRSGA------------ 152
            :|:|.|.....|.|..|....|.|        .|:..::::      |..|||
  Fly     7 SPSPPPKENPKENPNPGIKTTLKP--------FGKITVHNV------LSESGANALQQHIANQNT 57

Human   153 -----RGQGP-GAGRVGRATTPTGVSFYTSAAACPGGRA-----GGAQGEEVVLNPV-------- 198
                 |..|. ||.:...|:| |..:..:|....|.|.:     ...|.:::....|
  Fly    58 IIRKIRDFGMLGAVQSAAAST-TNTTPISSQRKRPLGESQKQNRHNQQNQQLSKTSVPAKKCKTN 121

Human   199 ---ALE--PQAGA--------PDGFFGEPDAFPMFTTNNRVKRRPSPYEMEITDGPHTKVVRRIF 250
               |:|  |:||.        .|..||.|..          |..|.|          ..|.||
  Fly   122 KKLAVERPPKAGTISHPHKSQSDQSFGTPGR----------KGLPLP----------QAVARR-- 164

Human   251 TNSRERWRQQNVNGAFAELRKLIPTHPPD------------KKLSKNEILRLAMKYINFLAKLLN 303
             |:|||.|.:.||..||.||:.||....:            |||||.|.||:|::||..|.|||
  Fly   165 -NARERNRVKQVNNGFALLREKIPEEVSEAFEAQGAGRGASKKLSKVETLRMAVEYIRSLEKLL- 227

Human   304 DQEEEGTQRAKTGKD-PVVGAGGGGGGGGGGAPPDDLLQDVLSPNSSCGSSLDGAASPDSYTEEP 367
                        |.| |.:.:.|...|.|     ||....:...........|.:.|.....|:.
  Fly   228 ------------GFDFPPLNSQGNSSGSG-----DDSFMFIKDEFDCLDEHFDDSLSNYEMDEQQ 275

Human   368 APKHTARS--LHPA----MLPA 383
            ..:.|...  |:|.    :||:
  Fly   276 TVQQTLSEDMLNPPQASDLLPS 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TAL1	XP_047285001.1	bHLH_TS_TAL1	244..308	CDD:381549	31/75 (41%)
ase	NP_476694.1	bHLH_TS_dAS-C_like	170..227	CDD:381587	22/56 (39%)