DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TAF10 and Taf10b

DIOPT Version :9

Sequence 1:	NP_006275.1	Gene:	TAF10 / 6881	HGNCID:	11543	Length:	218	Species:	Homo sapiens
Sequence 2:	NP_477418.1	Gene:	Taf10b / 33468	FlyBaseID:	FBgn0026324	Length:	146	Species:	Drosophila melanogaster

Alignment Length:	139	Identity:	77/139 - (55%)
Similarity:	94/139 - (67%)	Gaps:	10/139 - (7%)

- Green bases have known domain annotations that are detailed below.

Human    81 SAGGAAPPEGAISNGVYVLPSAANGDVKPVVSSTPLVDFLMQLEDYTPTIPDAVTGYYLNRAGFE 145
            |||||: ..|..|.|      ...||......|:.|.||:.|||||||.||||||.:|||..||:
  Fly    13 SAGGAS-SHGQSSGG------GGGGDRDRTTPSSHLSDFMSQLEDYTPLIPDAVTSHYLNMGGFQ 70

Human   146 ASDPRIIRLISLAAQKFISDIANDALQHCKMK---GTASGSSRSKSKDRKYTLTMEDLTPALSEY 207
            :.|.||:|||||||||::|||.:|||||.|.:   .|.:....||:||||:|||||||.|||::|
  Fly    71 SDDKRIVRLISLAAQKYMSDIIDDALQHSKARTHMQTTNTPGGSKAKDRKFTLTMEDLQPALADY 135

Human   208 GINVKKPHY 216
            ||||:|..|
  Fly   136 GINVRKVDY 144

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TAF10	NP_006275.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..85		3/3 (100%)
		TAF10	115..217	CDD:187739	66/105 (63%)
		[KR]-[STA]-K motif. /evidence=ECO:0000305\|PubMed:16415881	187..189		1/1 (100%)
Taf10b	NP_477418.1	TAF10	41..144	CDD:187739	65/102 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142508
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5162
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4536
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1478962at2759
OrthoFinder	1	1.000	-	-		FOG0004416
OrthoInspector	1	1.000	-	-		oto89225
orthoMCL	1	0.900	-	-		OOG6_103784
Panther	1	1.100	-	-	LDO	PTHR21242
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2306
SonicParanoid	1	1.000	-	-		X3131
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.790