DRSC/TRiP Functional Genomics Resources

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Protein Alignment TACR1 and TkR86C

DIOPT Version :9

Sequence 1:NP_001049.1 Gene:TACR1 / 6869 HGNCID:11526 Length:407 Species:Homo sapiens
Sequence 2:NP_001097741.1 Gene:TkR86C / 41286 FlyBaseID:FBgn0004841 Length:555 Species:Drosophila melanogaster


Alignment Length:310 Identity:119/310 - (38%)
Similarity:196/310 - (63%) Gaps:8/310 - (2%)


- Green bases have known domain annotations that are detailed below.


Human    22 PNQFVQPAW-QIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFN 85
            |.:..:..| |..:||..:.:::..::.||.:|:||:..|:.|||||||||:||:.|:..|::.|
  Fly    72 PTRPYELPWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLN 136

Human    86 TVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVV 150
            .|.||.:.::::|.:|..||..:||.....|..|::::.|::||||:||:|||:.|.|....:::
  Fly   137 CVFNFIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRII 201

Human   151 ICVIWVLALLLAFPQGYYSTTETM-----PSRVVCMIEWPE--HPNKIYEKVYHICVTVLIYFLP 208
            :.:||.|:.:|:.|...||:..|.     .||.||.:.||:  :|..:.:..|::.:.||.|.:|
  Fly   202 LVLIWALSCVLSAPCLLYSSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIP 266

Human   209 LLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYI 273
            ::|:...|:::|..||.|...|:::||..|.:.:|||||:|.|.:|..|||||||:|:||:..|.
  Fly   267 MIVMLICYSLMGRVLWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYH 331

Human   274 NPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCC 323
            |..:...|::|.:||...|||||:.|.||:||..:|.|||:.|:....||
  Fly   332 NNQVASTKYVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIICCC 381

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TACR1NP_001049.1 7tmA_NK1R 33..316 CDD:320668 113/289 (39%)
TM helix 1 35..59 CDD:320668 7/23 (30%)
TM helix 2 68..90 CDD:320668 10/21 (48%)
TM helix 3 106..128 CDD:320668 5/21 (24%)
TM helix 4 149..165 CDD:320668 4/15 (27%)
TM helix 5 194..217 CDD:320668 6/22 (27%)
TM helix 6 247..269 CDD:320668 13/21 (62%)
TM helix 7 284..309 CDD:320668 13/24 (54%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 364..407
TkR86CNP_001097741.1 7tm_4 92..376 CDD:304433 112/283 (40%)
7tm_1 100..363 CDD:278431 105/262 (40%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4219
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D314830at33208
OrthoFinder 1 1.000 - - FOG0000620
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3520
SonicParanoid 1 1.000 - - X257
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
87.810

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