Protein Alignment TACR1 and moody

DIOPT Version :10

• Sequence 1: NP_001049.1
• Gene: TACR1 / 6869
• HGNCID: 11526
• Length: 407
• Species: Homo sapiens
• Sequence 2: NP_569970.2
• Gene: moody / 31168
• FlyBaseID: FBgn0025631
• Length: 670
• Species: Drosophila melanogaster
• Alignment Length: 485
• Identity: 93/485 - (19%)
• Similarity: 163/485 - (33%)
• Gaps: 145/485 - (29%)

Human    32 IVLWAAAYT-VIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVH 95
            ::.:||..| :|::..:.||::.:..:|...::|.|...|:::|..|:....|..........|.
  Fly    35 LLTFAAVMTFLIMIVGICGNLLTVVALLKCPKVRNVAAAFIISLCIADLLFCALVLPFQGLRFVQ 99

Human    96 NEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATK-----VVICVIW 155
            ..|.:|...|:...|.....:..|:..:..:..:||:.|.|   ..|.|...|     |:|...|
  Fly   100 GTWRHGQVLCRLIPFIQYGNIGVSLLCIAMITINRYVMITH---HGLYARIYKRHWIAVMIAACW 161

Human   156 VLALLLAFPQ--------GYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVI 212
            :.:..:..|.        ||.|..:|      |.|...:|.:.....::     :..:.:|.|||
  Fly   162 LFSYGMQLPTLLGEWGRFGYDSRLQT------CSIMTDDHGHSSKTTLF-----ITAFVIPCLVI 215

Human   213 GYAYTVVGITLWASE---------------------------------------IPGDSSDRY-- 236
            ...|..:...:..||                                       :..|||..:
  Fly   216 IACYAKIFWVVHKSEQRLKRHATKQNSIPNNLRPLASTGSGALPSGAECQPSNRVSSDSSSSFSI 280

Human   237 ------------------HEQVSAKR---KVVKMMIVVVCTFAICWLPFHIFFLLP--YINPDLY 278
                              ..:|.|||   ::.||::.:..:|.:|:||..|..:..  ..:|.|:
  Fly   281 DVPETAPSGKQQPTRVKDQREVRAKRNEWRITKMVLAIFLSFVVCYLPITIVKVADKNVEHPSLH 345

Human   279 LKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCP---FISAGDYEGLEMKSTR 340
            :..:|      :::|   |...|||||..:|.::|..:|....|.|   .:..|...|....:.:
  Fly   346 ICSYI------LLYL---SACINPIIYVIMNKQYRKAYKTVVFCQPARLLLPFGKTNGASSAAEK 401

Human   341 YLQT--------------QGSVYKVSRLETTISTVVGAHEEEPED------------GP------ 373
            :..|              .|.....|...|...|...|..:.|.:            ||
  Fly   402 WKDTGLSNNHSRTIVSQMSGGTGAASGAGTATGTAAVAVMQTPPEVQQAQALEMVSRGPDLISKS 466

Human   374 --------KATPSSLDLTSNCSSRSDSKTM 395
                    ...||.|..|.| .|.|:|.|:
  Fly   467 NLPQPNVTPPPPSVLTATPN-GSNSNSLTL 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TACR1	NP_001049.1	7tmA_NK1R	33..316	CDD:320668	70/360 (19%)
		TM helix 1	34..60	CDD:320668	7/26 (27%)
		TM helix 2	67..93	CDD:320668	4/25 (16%)
		TM helix 3	105..135	CDD:320668	5/29 (17%)
		TM helix 4	146..167	CDD:320668	5/33 (15%)
		TM helix 5	193..222	CDD:320668	5/28 (18%)
		TM helix 6	241..271	CDD:320668	10/32 (31%)
		TM helix 7	284..309	CDD:320668	7/24 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..407		13/58 (22%)
moody	NP_569970.2	7tmA_GPR84-like	37..374	CDD:320338	70/359 (19%)
		TM helix 1	38..64	CDD:320338	7/25 (28%)
		TM helix 2	71..94	CDD:320338	4/22 (18%)
		TM helix 3	109..139	CDD:320338	5/29 (17%)
		TM helix 4	153..171	CDD:320338	3/17 (18%)
		TM helix 5	196..305	CDD:320338	11/113 (10%)
		TM helix 6	306..336	CDD:320338	8/29 (28%)
		TM helix 7	342..367	CDD:320338	10/33 (30%)