Protein Alignment TACR2 and TkR99D

DIOPT Version :9

• Sequence 1: NP_001048.2
• Gene: TACR2 / 6865
• HGNCID: 11527
• Length: 398
• Species: Homo sapiens
• Sequence 2: NP_001263092.1
• Gene: TkR99D / 43551
• FlyBaseID: FBgn0004622
• Length: 564
• Species: Drosophila melanogaster
• Alignment Length: 385
• Identity: 144/385 - (37%)
• Similarity: 219/385 - (56%)
• Gaps: 23/385 - (5%)

Human     5 DIVTEANISSGPE----SNTTGITAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILAHRRMR 65
            |:....::....|    |..||..||.:|.|:..||:..:..:|:||..||.||:||::..:|||
  Fly    69 DLPAVGDVEDAAEDAAASMETGSFAFVVPWWRQVLWSILFGGMVIVATGGNLIVVWIVMTTKRMR 133

Human    66 TVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAAD 130
            ||||||||||::||..:::.|..||:.|...:.|.||..:|.......:.::..|::::.||:.|
  Fly   134 TVTNYFIVNLSIADAMVSSLNVTFNYYYMLDSDWPFGEFYCKLSQFIAMLSICASVFTLMAISID 198

Human   131 RYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASP-QCFYSTVTMD----QGATKCVVAWPEDSG 190
            ||:||:.|.|||:|.....|:.|.|||.:..::.| ...|.|..:.    ...|.|...||:...
  Fly   199 RYVAIIRPLQPRMSKRCNLAIAAVIWLASTLISCPMMIIYRTEEVPVRGLSNRTVCYPEWPDGPT 263

Human   191 GKTLL--LYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLRHLQAMKKFVKTMV 253
            ..:.:  ||::::|.|.||||:..|.|.||.:|:.||.....| :.....:.::::.::.||.|:
  Fly   264 NHSTMESLYNILIIILTYFLPIVSMTVTYSRVGIELWGSKTIG-ECTPRQVENVRSKRRVVKMMI 327

Human   254 LVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGF 318
            :|||.|||||||:|.|||:.|....|....|||::|||::|||||::||||||||.:|.|||.||
  Fly   328 VVVLIFAICWLPFHSYFIITSCYPAITEAPFIQELYLAIYWLAMSNSMYNPIIYCWMNSRFRYGF 392

Human   319 RLAFRCCPWV---TPTKEDKLELTPTTSLS-----TRVNRCHTKETLFMAGDTAPSEATS 370
            ::.||.|.:|   |.....:..||...|.|     .|:.|..|::::..   |.||...|
  Fly   393 KMVFRWCLFVRVGTEPFSRRENLTSRYSCSGSPDHNRIKRNDTQKSILY---TCPSSPKS 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TACR2	NP_001048.2	7tm_4	42..>168	CDD:304433	51/126 (40%)
		7tm_1	50..307	CDD:278431	105/263 (40%)
TkR99D	NP_001263092.1	7tm_4	113..396	CDD:304433	116/283 (41%)
		7tm_1	118..381	CDD:278431	105/263 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147241
Domainoid	1	1.000	269	1.000	Domainoid score	I1855
eggNOG	1	0.900	-	-		E1_KOG4219
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	329	1.000	Inparanoid score	I2456
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45276
OrthoDB	1	1.010	-	-		D314830at33208
OrthoFinder	1	1.000	-	-		FOG0000620
OrthoInspector	1	1.000	-	-		otm41142
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3520
SonicParanoid	1	1.000	-	-		X257
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.800