Protein Alignment TACR2 and TkR86C

DIOPT Version :9

• Sequence 1: NP_001048.2
• Gene: TACR2 / 6865
• HGNCID: 11527
• Length: 398
• Species: Homo sapiens
• Sequence 2: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Alignment Length: 343
• Identity: 123/343 - (35%)
• Similarity: 199/343 - (58%)
• Gaps: 24/343 - (6%)

Human    26 FSMPSWQLALWATAYLALVLVAVTGNAIVIWIILAHRRMRTVTNYFIVNLALADLCMAAFNAAFN 90
            :.:|..|..:||..:..::.||:.||.||:||:..||.||||||||::||::|||.|::.|..||
  Fly    76 YELPWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFN 140

Human    91 FVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGI 155
            |::..::.|.||..:|...|......:..|::::.||:.|||:|||||.:.|.|....:.::..|
  Fly   141 FIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIILVLI 205

Human   156 WLVALALASPQCFYSTVTM-----DQGATKCVVAWPEDSGGKTL--LLYHLVVIALIYFLPLAVM 213
            |.::..|::|...||::..     .:..|.|.:.||:.....::  ..|:|:::.|.|.:|:.||
  Fly   206 WALSCVLSAPCLLYSSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVM 270

Human   214 FVAYSVIGLTLWRRAVPGHQAHGANL-RHLQAMK---KFVKTMVLVVLTFAICWLPYHLYFILGS 274
            .:.||::|..||     |.::.|.|. |.:::||   |.|:..:.:|..||||||||||:||...
  Fly   271 LICYSLMGRVLW-----GSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAY 330

Human   275 FQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGF-RLAFRCCPWVTPTKEDKLEL 338
            ....:...|::|.:||..:|||||:.|.||:||..:|.|||..| |:...||..:|..:.|
  Fly   331 HNNQVASTKYVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIICCCCVGLTRHRFD---- 391

Human   339 TPTTSLSTR--VNRCHTK 354
            :|.:.|:.:  .|| ||:
  Fly   392 SPKSRLTNKNSSNR-HTR 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TACR2	NP_001048.2	7tm_4	42..>168	CDD:304433	50/125 (40%)
		7tm_1	50..307	CDD:278431	99/267 (37%)
TkR86C	NP_001097741.1	7tm_4	92..376	CDD:304433	108/288 (38%)
		7tm_1	100..363	CDD:278431	99/267 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147240
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4219
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55548
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D314830at33208
OrthoFinder	1	1.000	-	-		FOG0000620
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3520
SonicParanoid	1	1.000	-	-		X257
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.740