Protein Alignment TBXT and bi

DIOPT Version :9

• Sequence 1: NP_001353214.1
• Gene: TBXT / 6862
• HGNCID: 11515
• Length: 436
• Species: Homo sapiens
• Sequence 2: NP_001259238.1
• Gene: bi / 31379
• FlyBaseID: FBgn0000179
• Length: 1023
• Species: Drosophila melanogaster
• Alignment Length: 521
• Identity: 165/521 - (31%)
• Similarity: 230/521 - (44%)
• Gaps: 114/521 - (21%)

Human     1 MSSPGTESAGKSLQYRVDHLLSAVENELQAGSEKGDPTERELRVGLEESELWLRFKELTNEMIVT 65
            :.|..|.:....|...|.|.|......|:|...:.|....:.:|.||..:||.:|.:|..||::|
  Fly   287 LGSAYTTAEDVVLASAVAHQLHPAMRPLRALQPEDDGVVDDPKVTLEGKDLWEKFHKLGTEMVIT 351

Human    66 KNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSP 130
            |:||:|||.:|..|||||..|.|..|||.||||::|:|:.|..|:..||.:|:.|..:|||||||
  Fly   352 KSGRQMFPQMKFRVSGLDAKAKYILLLDIVAADDYRYKFHNSRWMVAGKADPEMPKRMYIHPDSP 416

Human   131 NFGAHWMKAPVSFSKVKLTNKLNGG----GQIMLNSLHKYEPRIHIVRVGG----PQRMITSHCF 187
            ..|..||:..|||.|:||||.::..    ...:|||:|||:||.|:||...    |.....::.|
  Fly   417 TTGEQWMQKVVSFHKLKLTNNISDKHGFVSTTILNSMHKYQPRFHLVRANDILKLPYSTFRTYVF 481

Human   188 PETQFIAVTAYQNEEITALKIKYNPFAKAFLD--AKERSDHKEMMEEPG---DSQQPGY-SQSGG 246
            .||:||||||||||:||.|||..|||||.|.|  |.:|...:.:|...|   |...|.: |.|..
  Fly   482 KETEFIAVTAYQNEKITQLKIDNNPFAKGFRDTGAGKREKKQALMSNRGSDSDKLNPTHVSSSRA 546

Human   247 WLLPGTSTLCPPANPH--------------------PQFGGALSLPSTHSCDRYPTLRSHRSSPY 291
            .|..|.:...|..:||                    ||   :..||.:||..:.
  Fly   547 PLHLGHAGRPPHLHPHAALLDNQQDDDDKLLDVVGPPQ---SPLLPLSHSLQQM----------- 597

Human   292 PSPYAHRNNSPTYSDNSPACLSMLQSHDNWSSLGMPAHPSMLPVSHNASPP-------------- 342
               :||:::         |.|:...:|...:..|...|.:....:.:|...
  Fly   598 ---HAHQHS---------AALAAWFNHLAGAGAGASEHAAAAAANASAEDALRRRLQADADVERD 650

Human   343 -TSSSQYPSLWSVSNGAVTP----------GSQAAAVSNGL---GAQF-----FRGSPAHYTPLT 388
             :.||...|:...:.||..|          |:.|||.:.||   |..:     ..|.|.|.:|..
  Fly   651 GSDSSCSESVGGSTGGAFRPTSTGSPKEAVGAAAAAAAAGLNPGGGSYPSPNISVGPPIHPSPHL 715

Human   389 HPVSAPSSSGSPLYEG------AAAATD--------IVDSQYDAAAQGRLI-------ASWTPVS 432
            .|...|.....|.:.|      ||||..        :.::|...|||...:       |..||||
  Fly   716 LPYLYPHGLYPPPHLGLLHNPAAAAAMSPAGLNPGLLFNAQLALAAQHPALFGHAYAAAGHTPVS 780

Human   433 P 433
            |
  Fly   781 P 781

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBXT	NP_001353214.1	T-box	44..219	CDD:307177	93/182 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	280..309		2/28 (7%)
bi	NP_001259238.1	Optomotor-blind	<260..318	CDD:287988	8/30 (27%)
		T-box	330..513	CDD:279278	93/182 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810