Protein Alignment SYT4 and Syt7

DIOPT Version :9

• Sequence 1: NP_065834.1
• Gene: SYT4 / 6860
• HGNCID: 11512
• Length: 425
• Species: Homo sapiens
• Sequence 2: NP_726557.3
• Gene: Syt7 / 43783
• FlyBaseID: FBgn0039900
• Length: 416
• Species: Drosophila melanogaster
• Alignment Length: 443
• Identity: 144/443 - (32%)
• Similarity: 234/443 - (52%)
• Gaps: 72/443 - (16%)

Human    17 VVGIFSAFGLVFTVSLF---AWICCQRKSSKSNKTPPYKFVHVLKGVDIYPENLNSKKKFGADDK 78
            ::...:..||:.|::||   .::..:.|.|:.....|.:           .|..:|.....|.|.
  Fly     6 LIACLAILGLIITIALFLAGGYLWWRHKRSQLQFIEPNE-----------DEESSSYSLRAAQDI 59

Human    79 NEVKN---KPAVP---------KNSLHLDLE-----KRDLNGNFPKTNLKP------GSPSDLEN 120
            .:..|   ||.||         :|:::..|.     :..|.|....:..||      |:|.|
  Fly    60 VDSGNPPTKPQVPVAHAITTPLQNNINRKLNGFLSLRTPLIGGSGASQTKPQIISSVGNPGD--- 121

Human   121 ATPKLFLEGEKESVSPESLKSSTSLT-----SEEKQEKLGTLFFSLEYNFERKAFVVNIKEARGL 180
                        ..:.:|...|.|:|     |.:..|.:|.:.|||||:|:....::.:.:.:.|
  Fly   122 ------------GTTKDSANKSISMTDMYLDSTDPSENVGQIHFSLEYDFQNTTLILKVLQGKEL 174

Human   181 PAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSF 245
            ||.| .|.|||||:::|:||:|||:::|::.|:||:|.::|||.|.|.|..::|...||..:..:
  Fly   175 PAKD-LSGTSDPYVRVTLLPDKKHRLETKIKRRTLNPRWNETFYFEGFPIQKLQSRVLHLHVFDY 238

Human   246 DRFSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGR---GELLISLCYQSTTNTLTVV 307
            |||||||.||||.:||..::.: ||....:.:      |...:   ||||.||||..:.:.||:.
  Fly   239 DRFSRDDSIGEVFLPLCQVDFA-GKQSFWKAL------KPPAKDKCGELLSSLCYHPSNSILTLT 296

Human   308 VLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISV 372
            ::|||:|...|::|.|||||||.|....||:.|:||.:..||.|.||||.|.|::|.|.:.:.|:
  Fly   297 LIKARNLKAKDINGKSDPYVKVWLQFGDKRVEKRKTPIFTCTLNPVFNESFSFNVPWEKIRECSL 361

Human   373 EFLVLDSERGSRNEVIGQLVLGAAAEGTGG---EHWKEICDYPRRQIAKWHVL 422
            :.:|:|.:...|||:||:::| |...|:|.   :||:::...||:.:.:||.|
  Fly   362 DVMVMDFDNIGRNELIGRILL-AGKNGSGASETKHWQDMISKPRQTVVQWHRL 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SYT4	NP_065834.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	73..93		8/31 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	127..147		4/24 (17%)
		C2A_Synaptotagmin-4-11	153..279	CDD:176034	52/125 (42%)
		C2B_Synaptotagmin-4	288..423	CDD:176049	59/141 (42%)
Syt7	NP_726557.3	C2A_Synaptotagmin-7	147..271	CDD:176032	52/131 (40%)
		C2B_Synaptotagmin-7	277..414	CDD:176050	59/138 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920