Protein Alignment Atp8b2 and CG33298

DIOPT Version :9

• Sequence 1: XP_038959700.1
• Gene: Atp8b2 / 685152
• RGDID: 1597731
• Length: 1359
• Species: Rattus norvegicus
• Sequence 2: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Alignment Length: 1425
• Identity: 443/1425 - (31%)
• Similarity: 692/1425 - (48%)
• Gaps: 290/1425 - (20%)

  Rat    72 VTSAPRPKLTQSSGPGPRGVGRRARLLWGAGACGQRSRAPPPQPPAWAGRGRRAERRARSAKEKV 136
            :|.:| |.....:|.|...||.:...:...|...:.:|.|.....|..|||   ..|..|..|.:
  Fly   136 ITDSP-PGSAAPAGRGHSRVGSKTDFILPPGHKEEPAREPSAPTSATGGRG---HSRQASRSESI 196

  Rat   137 HGEVEGSRGSPVLSIVLTGLRGLPWIAGTLLGEMALC-------AKKR-----------PPEEER 183
            :              .|......||     ...:.||       .::|           ||:..:
  Fly   197 Y--------------TLRRTEAPPW-----WKRLTLCNYNTGDKFEERSYRTVVPNHTVPPKTPK 242

  Rat   184 RARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWF 248
            |...|.       |:..|.|:|:||.:|:|:|.||.|||..|||.||:|:::|..:|:||:....
  Fly   243 RDHPNG-------QFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKE 300

  Rat   249 TTIVPLVLVLTITAVKDATDDYFRHKSDNQVNSRHSQVLINGVLQ---QEQWMNVCVGDIIKLEN 310
            ..::|::.||.:|||||..:|..|..||.::|:...:| .:|..:   :.:|..:.||||:.|.|
  Fly   301 VAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRV-YDGETERYKKVKWQELRVGDIVHLSN 364

  Rat   311 NQFVAADLLLLSSSEPHGLCYIETSELDGETNMKVRQAIPVTSELGDISQLAKFDGEVICEPPNN 375
            |:.|.||:|||.:|:|.|:|||:|.:||||||:|.|:.:....|:..|...:||...|..:.|..
  Fly   365 NETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIFVPSKFVSRVEADAPTT 429

  Rat   376 KLDKFSGAL-YWKGNKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKRTSID 439
            ||.:|.||| :..|.:.|:|.:.:|||...|:||::..|:|::||.:||.|.|:...::||:.::
  Fly   430 KLYRFHGALIHPTGERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVE 494

  Rat   440 RLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGTRFQV-YLPWDEAVDSAFFSGFLSFWSYIIIL 503
            :.||..|:|....|:.:.|:.|||..:|.... |.|.| |||.::.  :|.......||:||:||
  Fly   495 QQMNIDVIWCVIILLILCVVGAIGCRMWLSSF-THFPVPYLPPNKL--TANMESMWIFWTYIVIL 556

  Rat   504 NTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQ 568
            ..::|:||||::|:.::...:.|:.:..:|..:.....|.|...:.|||||:::||:|||||||:
  Fly   557 QVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTE 621

  Rat   569 NIMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDFSFNPLADKKFLFWDPSLLEAVKMGDPHT 633
            |.|:|.:|.:||..|......|.........|.|      ||.....|..|.:.|.......||.
  Fly   622 NKMIFRRCVVNGSDYNHPPSELEKIYSKPGAPAP------PLIPNDNLNSDMAQLTQGTYLTPHA 680

  Rat   634 ---HEFFRLLSLCHTVM------------------------------------------------ 647
               .||..:|::|:||:
  Fly   681 QRIQEFLVVLAICNTVIVGAAPHRDMMNASGIIEVQQIGNSPANLKHGKQRQKLLASSTSTTTTT 745

  Rat   648 ----------------------------------------------------------------S 648
                                                                            |
  Fly   746 TIINGPTTQPQVVSIPADRYIRLAESRSVTPSPPPNLLFALPAQSHQPTLSPISSSAESSPNSES 810

  Rat   649 EE-----KNE-------------------------------------------GELY-------- 657
            |.     ||:                                           |.:|
  Fly   811 ESPSPPMKNKSLSNSISPTGRAKAVINSKITSIATFLNAKTQGKRMKLPSSKTGTIYRTADGRPL 875

  Rat   658 YKAQSPDEGALVTAARNFGFVFRSRTPKTVTVH--ELGTSITYQLLAILDFNNIRKRMSVIVRN- 719
            |:|:||||.|||.||.::.....:|:|..:.|.  ..|.:..|::|.:|.|::.||.||::||.
  Fly   876 YEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQI 940

  Rat   720 PEGKIRLYCKGADT----ILLDRLHPSTQELLNSTTDH-LNEYAGDGLRTLVLAYKDLDEEYYEE 779
            ...:|.||.||||:    :|:...|.|.:.:|...|.. |:.||.:|||.||:|.:.|:...|.:
  Fly   941 GSQEIVLYTKGADSSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTD 1005

  Rat   780 WARRRLQASLAQDSREDRLASIYEEVESDMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTG 844
            |..|..:..::.::||.||...:.::||::.|||||.|||:||.|||||||.|..|.|.:|||||
  Fly  1006 WWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTG 1070

  Rat   845 DKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKARKKMVDSSHAVGNGFTYQGNLSSS 909
            ||.|||:||.||.|:.|..|                ||.:...:..|::....|  .|..::.:.
  Fly  1071 DKPETAINIAYSAKLFTQQM----------------ELIRLTARSRDAAETAIN--FYLTDMEND 1117

  Rat   910 KLTSVL----EAVAGEYALVINGHSLAHALE--ADMELEFLETACACKAVICCRVTPLQKAQVVE 968
            |.||.|    .....:.|||::|.:|...|:  :.:.|.||..:..|.:|:|||.||||||.:|:
  Fly  1118 KTTSTLGYGQSLRKKQRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVK 1182

  Rat   969 LVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWS 1033
            :||:.....||||||||||||||:.|.:|||||||||:|||:|:|::..:|::|:||||.||.|.
  Fly  1183 VVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWC 1247

  Rat  1034 YLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVP 1098
            |.|:.:.:.||||||.||..:.||:..:||||.|.:.||.::.|||:::||||.||:||:|:.|.
  Fly  1248 YDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVA 1312

  Rat  1099 EQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFAEATRDDGTQLADYQSFA 1163
            |...::.|.||:.|:|.:.:...:|::.:...:|.|:::||:....:||:  |.|     ...|.
  Fly  1313 EDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAES--DVG-----IWEFG 1370

  Rat  1164 VTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVY--FAILF---AMHSNGLFDMFPNQFRFV 1223
            .|:..|.:....|...::...||.::...|..||..:  |||::   .|:..|:...:...|...
  Fly  1371 TTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSFYLFAIVYDSVCMNCFGVRSSYWVIFVCF 1435

  Rat  1224 GNAQNTLAQPTVWLTIVLTTAVCIMPVVAFRFLRLSLKPDLSDTVRYTQLVRKKQKAQHR 1283
            .:|.:       ||.|:|:|.|.::|.:....:|:||.||.|     |:::.:.::.:.|
  Fly  1436 ASAVH-------WLVIMLSTVVAVLPRLLLTTVRISLCPDDS-----TKVILQSKRERSR 1483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atp8b2	XP_038959700.1	P-type_ATPase_APLT_Dnf-like	200..1141	CDD:319770	380/1130 (34%)
CG33298	NP_995666.1	PhoLip_ATPase_N	249..299	CDD:292826	24/49 (49%)
		ATPase-Plipid	250..1473	CDD:273734	414/1269 (33%)
		E1-E2_ATPase	302..>394	CDD:278548	38/92 (41%)
		Cation_ATPase	<880..965	CDD:289987	31/84 (37%)
		HAD_like	<1177..1240	CDD:304363	37/62 (60%)
		PhoLip_ATPase_C	1223..1468	CDD:292829	85/258 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53737
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	1	1.000	-	-		FOG0000076
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.930