Protein Alignment VAMP2 and Syb

DIOPT Version :10

• Sequence 1: NP_001317054.1
• Gene: VAMP2 / 6844
• HGNCID: 12643
• Length: 118
• Species: Homo sapiens
• Sequence 2: NP_001137633.1
• Gene: Syb / 36080
• FlyBaseID: FBgn0003660
• Length: 152
• Species: Drosophila melanogaster
• Alignment Length: 125
• Identity: 70/125 - (56%)
• Similarity: 84/125 - (67%)
• Gaps: 22/125 - (17%)

Human    10 APPAAPAGEGG---PPAPPP-----------------NLTSNRRLQQTQAQVDEVVDIMRVNVDK 54
            ||  :|:|...   |..|||                 |..:.::||||||:|||||.||||||:|
  Fly     6 AP--SPSGSNNNDFPILPPPPNANDNYNQFGDHQIRNNNAAQKKLQQTQAKVDEVVGIMRVNVEK 68

Human    55 VLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIV 114
            |||||||||||.:|||.|:.||||||..|.|||||.||.|:|||||||||..::|||::|
  Fly    69 VLERDQKLSELGERADQLEQGASQFEQQAGKLKRKQWWANMKMMIILGVIAVVLLIIVLV 128

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VAMP2	NP_001317054.1	R-SNARE_VAMP2	32..94	CDD:277223	47/61 (77%)
Syb	NP_001137633.1	Synaptobrevin	44..130	CDD:395764	61/85 (72%)