DRSC/TRiP Functional Genomics Resources

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Protein Alignment SURF6 and Surf6

DIOPT Version :10

Sequence 1:NP_006744.2 Gene:SURF6 / 6838 HGNCID:11478 Length:361 Species:Homo sapiens
Sequence 2:NP_524408.1 Gene:Surf6 / 42370 FlyBaseID:FBgn0038746 Length:324 Species:Drosophila melanogaster


Alignment Length:358 Identity:81/358 - (22%)
Similarity:155/358 - (43%) Gaps:93/358 - (25%)


- Green bases have known domain annotations that are detailed below.


Human    51 TQKKFRK--REEKAAEHKAKSLGEKS--PAAS------------------GARRPEAAKEEAAWA 93
            ||.:..|  |||...||......||.  ||.:                  ..:..|...||...:
  Fly     2 TQAEIVKCLREEYEIEHNKDQKPEKEDLPAITKKFYQRVLELLTIHKVPYSKQEDEETYEEYLLS 66

Human    94 -SSSAGNPADGLATEPESVFALDVLRQRLHEKIQEARGQGSAKELSPAALEKRRRRKQ----ERD 153
             :..:||.                 :::...|::.........|...|:::.:.|:|:    ||.
  Fly    67 DTEESGNK-----------------KKKQQGKLKNQDSDDEDVEARIASIKNKLRQKKGPTTERQ 114

Human   154 RKKRKRKEL-------------------------RAKEKARKAEEATE-AQEVVEATPEGACTEP 192
            :|:|:.|:|                         :.|....|:|:.|| ::|.::...    .:|
  Fly   115 QKRRESKKLKRSKGVQKLLLSSAKNLKNENVKHQKLKNGVVKSEQETEDSKEQIQPVK----VQP 175

Human   193 --REPPGLIFNKVEVSEDEPASKAQRRKEKRQRVKGNLTPLTGRNYRQLLERLQARQSRLDELRG 255
              .:...::::||:.:.: |..||::               :.:|.:::|::|:..:..|.|||.
  Fly   176 VYNQEAKIVYSKVDFAAN-PGGKAKK---------------SHQNPKEILKKLRDTKKHLTELRE 224

Human   256 QDE-GKAQELEAKMKWTNLLYKAEGVKIRDDERLLQEALKRKEKRRAQRQRRWEKRTAGVVEKMQ 319
            |.| .||.|::..:.|.|...|.||.|::||.:|||:|:|::...:.:.:.:|.:|...|....:
  Fly   225 QGETDKAAEIQTDIAWRNAFDKVEGKKVKDDTKLLQKAIKKRRVEKKKSKTKWTERKQKVEHDKE 289

Human   320 QRQDRRRQNLRRKKAARAERRLLRARKKGRILP 352
            :||.:|::||.::...:..|:|..|.|:|||:|
  Fly   290 KRQKKRQENLEKRSKDKKNRKLKTASKRGRIIP 322

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SURF6NP_006744.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 20..106 17/77 (22%)
Nuclear localization signal. /evidence=ECO:0000255 45..49
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 125..230 22/136 (16%)
Nuclear localization signal. /evidence=ECO:0000255 154..158 1/3 (33%)
SURF6 166..318 CDD:461491 39/155 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 299..334 8/34 (24%)
Surf6NP_524408.1 SURF6 156..312 CDD:461491 45/175 (26%)
Blue background indicates that the domain is not in the aligned region.

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