Protein Alignment SURF1 and SHY1

DIOPT Version :10

• Sequence 1: NP_003163.1
• Gene: SURF1 / 6834
• HGNCID: 11474
• Length: 300
• Species: Homo sapiens
• Sequence 2: NP_011627.1
• Gene: SHY1 / 853009
• SGDID: S000003344
• Length: 389
• Species: Saccharomyces cerevisiae
• Alignment Length: 341
• Identity: 92/341 - (26%)
• Similarity: 145/341 - (42%)
• Gaps: 99/341 - (29%)

Human    37 VAWRPSRCGSSAAEASATKAEDDSFLQWVLL----LIPVTAFGLGTWQVQRRKWKLNLIAELESR 97
            |.|:|.:.|.|..:.|   ..:.||.:.::|    .:|:.:|.||||||:|.|||..|||..|::
Yeast    47 VDWKPIKTGKSPNDDS---RRERSFGKKIVLGLMFAMPIISFYLGTWQVRRLKWKTKLIAACETK 108

Human    98 VLAEPVPLPAD--PMELKNLEYRPVKVRGCFDHSKELYMMPRTMVDPVREAREGGLISSSTQSGA 160
            :..||:|||..  |...::.|||.|.:.|.|.|::|:::.||         ::.|      :.|.
Yeast   109 LTYEPIPLPKSFTPDMCEDWEYRKVILTGHFLHNEEMFVGPR---------KKNG------EKGY 158

Human   161 YVVTPFHCTDLGVTILVNRGFVPRKKVNPETRQKGQI----EGEVDLIGMVRLTETRQPFV-PEN 220
            ::.|||...|.|..:|:.||::..:||.|::|....:    |..:.::.:||..:.|.... .:.
Yeast   159 FLFTPFIRDDTGEKVLIERGWISEEKVAPDSRNLHHLSLPQEEHLKVVCLVRPPKKRGSLQWAKK 223

Human   221 NPERNHWHYRDLEAMARITGAEPIFIDANF----------------------------------- 250
            :|....|...|:..|||.:|..||...|.:
Yeast   224 DPNSRLWQVPDIYDMARSSGCTPIQFQALYDMKDHPIIEEHTRNEASQNNSTSSLWKFWKREPTT 288

Human   251 --------------------------------QSTVPGGPIGGQTRVTLRNEHLQYIVTWYGLS- 282
                                            |....|.|||.:..:.|:|.||||:|||||||
Yeast   289 AVNGTQAVDNNTSKPRSRQEMPTDQTIEFDERQFIKAGVPIGRKPTIDLKNNHLQYLVTWYGLSF 353

Human   283 AATSYL--WFKKFLRG 296
            .:|.:|  ..:|..||
Yeast   354 LSTIFLIVALRKAKRG 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SURF1	NP_003163.1	SURF1	74..288	CDD:119401	78/288 (27%)
SHY1	NP_011627.1	SURF1	78..353	CDD:460447	77/289 (27%)