DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment STYX and puc

DIOPT Version :9

Sequence 1:NP_001124173.1 Gene:STYX / 6815 HGNCID:11447 Length:223 Species:Homo sapiens
Sequence 2:NP_524273.1 Gene:puc / 40958 FlyBaseID:FBgn0243512 Length:476 Species:Drosophila melanogaster


Alignment Length:159 Identity:52/159 - (32%)
Similarity:81/159 - (50%) Gaps:16/159 - (10%)


- Green bases have known domain annotations that are detailed below.


Human    66 NIEANFI------KPNFQQL--FRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNA 122
            ::.||.:      .||...|  .:|:.:..:|.|.:||.::|....:||:.:.:.|.:||:|.:|
  Fly   154 SVGANCVLNVTCQSPNESHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHA 218

Human   123 GISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYE-----AIYLAKLTIQM 182
            ||||||...|||:|....:...:|:..|:..|..|:||..|:.||.|.|     :..||..|..:
  Fly   219 GISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNLRKSGVLAPATPHL 283

Human   183 MSPLQIERSLSVHSGTTGS--LKRTHEEE 209
            .||.. ..|.||...|..|  :::..|||
  Fly   284 NSPSN-PSSSSVGLSTQSSQLVEQPEEEE 311

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
STYXNP_001124173.1 DSP_STYX 25..175 CDD:350372 39/121 (32%)
Interaction with FBXW7. /evidence=ECO:0000269|PubMed:28007894 76..78 0/1 (0%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 197..223 5/15 (33%)
pucNP_524273.1 DSPc 133..267 CDD:238073 38/112 (34%)
CDC14 <193..272 CDD:225297 29/78 (37%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1716
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1576308at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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