DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rnf133 and SPAC57A7.09

DIOPT Version :9

Sequence 1:	NP_001037743.1	Gene:	Rnf133 / 681395	RGDID:	1596695	Length:	381	Species:	Rattus norvegicus
Sequence 2:	NP_593372.1	Gene:	SPAC57A7.09 / 2542187	PomBaseID:	SPAC57A7.09	Length:	372	Species:	Schizosaccharomyces pombe

Alignment Length:	247	Identity:	58/247 - (23%)
Similarity:	91/247 - (36%)	Gaps:	76/247 - (30%)

- Green bases have known domain annotations that are detailed below.

  Rat   104 LIERGGCAFTQKIKVASENGARGVIIYNFPGTGNQVFPMSHQAFEDIVVVMIGNVKGMEILHLIR 168
            |::||.|.:..|...|...|.:|||:      |:...|.|.:....:....:...|
pombe   146 LVQRGKCTYFDKALEAQRLGFKGVIV------GDNRSPSSFRLHYMVAPDKVDESK--------- 195

  Rat   169 KGVHV-TVMVEVGRKHVIW-------------------LNHYFVSF---------MIVTTATLA- 203
              ||: ::.|.....:::|                   |...|..|         |::|...||
pombe   196 --VHIPSLFVSTSSYNLLWSDLLHSYRQPLKLYAKPEELGDMFWPFLLCFSPSIIMLITVQALAI 258

  Rat   204 ------YFTFYHIRRLWVARIEDRRWKRLTRELKKAF-------------GQLQVRILKEGDEEV 249
                  |.|....||.    |||...:.::||   .|             |:| |.::.|.....
pombe   259 RKFIRTYRTKSKTRRF----IEDLPSRTISRE---GFYSEEEEIENSTQNGEL-VPLMDESTRRA 315

  Rat   250 SPNADSCVICFEAYKPNEIVRILTCKHFFHKNCIDPWILAH-GTCPMCKCDI 300
            :...: ||||.|::...:.|..|.|||.||:.||..||:.: ..||.|..::
pombe   316 TFGVE-CVICLESFTKGDKVVALPCKHEFHRPCIAKWIVDYRHACPTCNTEV 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rnf133	NP_001037743.1	PA_GRAIL_like	43..177	CDD:239037	16/73 (22%)
		HRD1	<183..>368	CDD:227568	41/167 (25%)
		RING-H2_RNF128_like	254..302	CDD:319716	19/48 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	340..381
SPAC57A7.09	NP_593372.1	COG5540	1..369	CDD:227827	58/247 (23%)
		Peptidases_S8_S53	<144..211	CDD:299169	17/81 (21%)
		zf-RING_2	320..362	CDD:290367	18/42 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm64279
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910