DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galntl5 and Pgant9

DIOPT Version :9

Sequence 1:	NP_080725.2	Gene:	Galntl5 / 67909	MGIID:	1915159	Length:	431	Species:	Mus musculus
Sequence 2:	NP_001097342.1	Gene:	Pgant9 / 246627	FlyBaseID:	FBgn0050463	Length:	650	Species:	Drosophila melanogaster

Alignment Length:	401	Identity:	165/401 - (41%)
Similarity:	234/401 - (58%)	Gaps:	30/401 - (7%)

- Green bases have known domain annotations that are detailed below.

Mouse    31 QEDM---------LENEKEELLKKRSLGKNAHQQTRHSEDVTHDEVNFSDPELIQGLRRYGLNAI 86
            |||.         .|....||.|...|.|....:.:.:.|              .|..:...|..
  Fly   129 QEDSKKVIDPPANFEENPGELGKPVRLPKEMSDEMKKAVD--------------DGWTKNAFNQY 179

Mouse    87 MSRRLGIEREVPDSRDKICQ-QKHYPFNLPTASIIICFYNEEFNTLLRAVSSVVNLSPQHLLEEI 150
            :|..:.:.|.:||.||..|: :..|..|||...:||||:||.:..|||.|.||::.||:||:.:|
  Fly   180 VSDLISVHRTLPDPRDAWCKDEARYLTNLPKTDVIICFHNEAWTVLLRTVHSVLDRSPEHLIGKI 244

Mouse   151 ILVDDMSEFDDLKDKLDYYLEIFRGKVKLIRNKKREGLIRSKMIGASRASGDILVFLDSHCEVNR 215
            |||||.|:...||.:|:.|...: .||::||.:|||||||::::||:.|...:|.:||||||...
  Fly   245 ILVDDYSDMPHLKRQLEDYFAAY-PKVQIIRGQKREGLIRARILGANHAKSPVLTYLDSHCECTE 308

Mouse   216 VWLEPLLHAIAKDHKMVVCPIIDVINELTLDYM---AAPIVRGAFDWNLNLRWDNVFAYELDGPE 277
            .||||||..||::...||||:||||::.||:|.   :..:..|.|||||...|..|...|.....
  Fly   309 GWLEPLLDRIARNSTTVVCPVIDVISDETLEYHYRDSGGVNVGGFDWNLQFSWHPVPERERKRHN 373

Mouse   278 GPSTPIRSPAMTGGIFAINRHYFNELGQYDNGMDICGGENVELSLRIWMCGGQLFILPCSRVGYN 342
            ..:.|:.||.|.||:|:|:|.:|:.||.||:|.||.||||:|||.:.|||||.|.|:|||.||:.
  Fly   374 STAEPVYSPTMAGGLFSIDREFFDRLGTYDSGFDIWGGENLELSFKTWMCGGTLEIVPCSHVGHI 438

Mouse   343 SKALSQHR-RANQSALSRNLLRVVHVWLDEYKGNFFLQRPSLTYVSCGNISERVELRKRLGCKSF 406
            .:..|.:: |:..:.|.:|.:|:..||:||| ..::..|........|::|:|.:||..|.||||
  Fly   439 FRKRSPYKWRSGVNVLKKNSVRLAEVWMDEY-SQYYYHRIGNDKGDWGDVSDRRKLRNDLKCKSF 502

Mouse   407 QWYLDNIFPEL 417
            :||||||:|||
  Fly   503 KWYLDNIYPEL 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galntl5	NP_080725.2	Catalytic subdomain A	114..224		56/109 (51%)
		pp-GalNAc-T	118..414	CDD:133004	138/299 (46%)
		Glyco_tranf_2_2	118..380	CDD:287123	122/265 (46%)
		Catalytic subdomain B	282..344		36/61 (59%)
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	126/272 (46%)
		pp-GalNAc-T	213..510	CDD:133004	138/298 (46%)
		Ricin_B_lectin	521..640	CDD:279046
		RICIN	523..642	CDD:238092
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842526
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750