Protein Alignment AURKA and aurka

DIOPT Version :9

• Sequence 1: XP_016883523.1
• Gene: AURKA / 6790
• HGNCID: 11393
• Length: 437
• Species: Homo sapiens
• Sequence 2: NP_001016570.1
• Gene: aurka / 549324
• XenbaseID: XB-GENE-853082
• Length: 415
• Species: Xenopus tropicalis
• Alignment Length: 405
• Identity: 268/405 - (66%)
• Similarity: 314/405 - (77%)
• Gaps: 16/405 - (3%)

Human    35 MDRS-KENCISGPVKATAP-VGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQAQK 97
            |:|: |||..|. ||...| :.||||:.|||....|...|..:..|||:|.|||..||:..||||
 Frog     1 MERAVKENLPSN-VKVFHPTMEGPKRIPVTQPPSTQVRPPGTAVSAQRILGPSNVPQRVVSQAQK 64

Human    98 -LVSSHKPVQNQKQKQLQATSVP----HPVSRPLN-NTQKSKQPLPSAPENNPEEELASKQ---- 152
             ::|:.|||.:.::...|....|    |...:|.. |..::.|....:...|.|::.::.|
 Frog    65 PVMSAQKPVMSTQKPMTQGPLRPVTHGHQAGKPQGPNENRTPQQTSHSSTPNVEKKGSTDQGKTL 129

Human   153 --KNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRRE 215
              ..||.||:||.|||||||||||||||||||||||::||||||||||||.||||||||||||||
 Frog   130 AVPKEEGKKKQWCLEDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKTQLEKAGVEHQLRRE 194

Human   216 VEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSY 280
            ||||||||||||||||||||||.||||||:|||.|.::|||||:::||||::|.||.:||.||.|
 Frog   195 VEIQSHLRHPNILRLYGYFHDAARVYLILDYAPGGELFRELQKVTRFDEQKSALYIKQLAEALLY 259

Human   281 CHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVD 345
            ||||.||||||||||||||:.||||||||||||||||||||||||||||||||||||||||||||
 Frog   260 CHSKNVIHRDIKPENLLLGANGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVD 324

Human   346 LWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLRE 410
            |||||||||||||||||||.:|:||||:|||:|||.:|.:|:||||||:|:||||||:.|..|:.
 Frog   325 LWSLGVLCYEFLVGKPPFETDTHQETYRRISKVEFQYPSYVSEGARDLVSKLLKHNPNHRLSLKG 389

Human   411 VLEHPWITANSS-KP 424
            |||||||..||: ||
 Frog   390 VLEHPWIIDNSAQKP 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AURKA	XP_016883523.1	None
aurka	NP_001016570.1	STKc_Aurora-A	140..397	CDD:271018	215/256 (84%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	445	1.000	Domainoid score	I4847
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2670
Inparanoid	1	1.050	508	1.000	Inparanoid score	I7583
NCBI	1	1.000	-	-
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177886at32523
OrthoFinder	1	1.000	-	-		FOG0000946
OrthoInspector	1	1.000	-	-		oto157318
Panther	1	1.100	-	-	LDO	PTHR24350
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X555
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.070