Protein Alignment AURKA and Aurka

DIOPT Version :9

• Sequence 1: XP_016883523.1
• Gene: AURKA / 6790
• HGNCID: 11393
• Length: 437
• Species: Homo sapiens
• Sequence 2: NP_695208.2
• Gene: Aurka / 261730
• RGDID: 628895
• Length: 397
• Species: Rattus norvegicus
• Alignment Length: 404
• Identity: 337/404 - (83%)
• Similarity: 353/404 - (87%)
• Gaps: 8/404 - (1%)

Human    35 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQAQKLV 99
            |||.||||:|.|||:|.|. ||||||||:|.|.|:|...:|||||||||||| |||:|.||||.|
  Rat     1 MDRCKENCVSRPVKSTVPF-GPKRVLVTEQIPSQHPGSASSGQAQRVLCPSN-SQRVPPQAQKPV 63

Human   100 SSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKNEESKKRQWAL 164
            :..|||    .|||.|.|.|.|.|| |:|.|||:||.|:|..||.|:|..|.||.|:||||||.|
  Rat    64 AGQKPV----LKQLPAASGPRPASR-LSNPQKSEQPQPAASGNNSEKEQTSIQKTEDSKKRQWTL 123

Human   165 EDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILR 229
            |||:||||||||||||||||||||||||||||||||.||||||||||||||||||||||||||||
  Rat   124 EDFDIGRPLGKGKFGNVYLAREKQSKFILALKVLFKVQLEKAGVEHQLRREVEIQSHLRHPNILR 188

Human   230 LYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPE 294
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   189 LYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPE 253

Human   295 NLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVG 359
            ||||||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   254 NLLLGSNGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVG 318

Human   360 KPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 424
            .|||||:||||||:||||||||||||||||||||||||||||.|||..|.||||||||.||||||
  Rat   319 MPPFEAHTYQETYRRISRVEFTFPDFVTEGARDLISRLLKHNSSQRLTLAEVLEHPWIKANSSKP 383

Human   425 SNCQN-KESASKQS 437
            ....| ||:.||.|
  Rat   384 PTGHNSKEATSKSS 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AURKA	XP_016883523.1	None
Aurka	NP_695208.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..118		76/123 (62%)
		STKc_Aurora-A	120..376	CDD:271018	244/255 (96%)
		Activation segment. /evidence=ECO:0000250|UniProtKB:O14965	273..286		12/12 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	378..397		11/18 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83680394
Domainoid	1	1.000	486	1.000	Domainoid score	I7729
eggNOG	1	0.900	-	-		E1_KOG0580
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2670
Inparanoid	1	1.050	651	1.000	Inparanoid score	I9458
NCBI	1	1.000	-	-
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D107829at9347
OrthoFinder	1	1.000	-	-		FOG0000946
OrthoInspector	1	1.000	-	-		oto141158
orthoMCL	1	0.900	-	-		OOG6_100573
Panther	1	1.100	-	-	LDO	PTHR24350
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X555
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	16.300