Protein Alignment STK4 and SPS1

DIOPT Version :10

• Sequence 1: NP_006273.1
• Gene: STK4 / 6789
• HGNCID: 11408
• Length: 487
• Species: Homo sapiens
• Sequence 2: NP_010811.1
• Gene: SPS1 / 852135
• SGDID: S000002931
• Length: 490
• Species: Saccharomyces cerevisiae
• Alignment Length: 290
• Identity: 125/290 - (43%)
• Similarity: 177/290 - (61%)
• Gaps: 16/290 - (5%)

Human    26 PEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVE---SDLQEIIKEISIMQQCDSPHVVK 87
            |.:::.:...:|.|::|.||||:.:.|.:|||||.|.:|   .|::.:.:||..:.:..||.:..
Yeast    14 PSKLYSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITN 78

Human    88 YYGSYFKNTDLWIVMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIK 151
            |..:..::..:||||||||.||.||:: |.....|.|::::.|:.....||:|||..||||||||
Yeast    79 YIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIK 143

Human   152 AGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI--QEIGYNCVADIWSLGITA 214
            |.|||||.||..||.||||:|.:..|: ||:|.:|||:||||||:  :..|||..|||||||||.
Yeast   144 AANILLNEEGMVKLGDFGVSGHIRSTL-KRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITT 207

Human   215 IEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHP 279
            .|:.:|.||.:...||:.:..:|...||..:.|  :||...|||..||||:|..|.:|..||...
Yeast   208 YELLKGLPPLSKYDPMKVMTNLPKRKPPKLQGP--FSDAAKDFVAGCLVKTPADRPSAYNLLSFE 270

Human   280 FVRSAKGVSILRDLINEAMDVKLKRQESQQ 309
            ||   |.::|    .|...||.|.:|:..|
Yeast   271 FV---KNITI----TNLKSDVDLIKQKKVQ 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STK4	NP_006273.1	STKc_MST1_2	26..281	CDD:132943	115/260 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	303..332		2/7 (29%)
		SARAH_MST1	432..480	CDD:439181
SPS1	NP_010811.1	STKc_MST3_like	16..291	CDD:270786	123/284 (43%)