Protein Alignment STK4 and Pak3

DIOPT Version :10

• Sequence 1: NP_006273.1
• Gene: STK4 / 6789
• HGNCID: 11408
• Length: 487
• Species: Homo sapiens
• Sequence 2: NP_001262638.1
• Gene: Pak3 / 41995
• FlyBaseID: FBgn0044826
• Length: 583
• Species: Drosophila melanogaster
• Alignment Length: 315
• Identity: 107/315 - (33%)
• Similarity: 171/315 - (54%)
• Gaps: 17/315 - (5%)

Human     2 ETVQLRNPPRRQLKKLDEDSLTK--------QPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAI 58
            ||: ||....::.:|.|.:...:        .|.|.:...:::|:|:.|.|:.|...:....||:
  Fly   258 ETI-LRRSKEKRAQKTDAEIYVELRAICNSDDPRERYKTTQEVGKGASGIVFIAADLQNESQVAV 321

Human    59 KQVPV--ESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNK 119
            |.:.:  :|....|:.||.:::..:..::|.:..:|....:  ||:||||...|.::|::  ...
  Fly   322 KTIDMKNQSSKDLILTEIRVLKDFNHKNLVNFLDAYLLEPEDQLWVVMEYMDGGPLTDVV--TET 384

Human   120 TLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTV 184
            .:.|.:||.:.:.||..:.:||....||||||:.|:||..:|..|:.|||....: :...||.|:
  Fly   385 VMKERQIACVCRETLYAISFLHAKGIIHRDIKSDNVLLGMDGSVKVTDFGFCANI-EGDEKRQTM 448

Human   185 IGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPEL 249
            :|||:||||||:....|....||||:||.||||.||:|||....|:||:::|..|..|..:..:.
  Fly   449 VGTPYWMAPEVVTRKKYGKKVDIWSIGIMAIEMIEGQPPYLYETPLRALYLIAANGRPDIKSWDK 513

Human   250 WSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSAKGVSILRDLINEAMDVKLKR 304
            .|.|..||:.:||....::||||.:||.|||:.....|..|...|..|..| |:|
  Fly   514 LSPNLQDFLDRCLQVEVDRRATADELLSHPFLNDCSEVKALVPNIKAAKKV-LRR 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STK4	NP_006273.1	STKc_MST1_2	26..281	CDD:132943	93/258 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	303..332		1/2 (50%)
		SARAH_MST1	432..480	CDD:439181
Pak3	NP_001262638.1	PBD	19..76	CDD:395634
		Protein Kinases, catalytic domain	288..545	CDD:473864	93/259 (36%)