Protein Alignment STK4 and mbt

DIOPT Version :10

• Sequence 1: NP_006273.1
• Gene: STK4 / 6789
• HGNCID: 11408
• Length: 487
• Species: Homo sapiens
• Sequence 2: NP_523375.2
• Gene: mbt / 32631
• FlyBaseID: FBgn0025743
• Length: 639
• Species: Drosophila melanogaster
• Alignment Length: 274
• Identity: 111/274 - (40%)
• Similarity: 166/274 - (60%)
• Gaps: 4/274 - (1%)

Human    26 PEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQE--IIKEISIMQQCDSPHVVKY 88
            |.|..|...|:||||.|:|..|..|.||:.||:|::.:....:.  :..|:.||:....|::|:.
  Fly   364 PRENLDHFNKIGEGSTGTVCIATDKSTGRQVAVKKMDLRKQQRRELLFNEVVIMRDYHHPNIVET 428

Human    89 YGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAG 153
            |.|:..|.:||:||||...|:::||:  .:..:.|::|||:.:..||.|.|||....||||||:.
  Fly   429 YSSFLVNDELWVVMEYLEGGALTDIV--THSRMDEEQIATVCKQCLKALAYLHSQGVIHRDIKSD 491

Human   154 NILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMA 218
            :|||..:|..||:|||...|::..:.||.:::|||:||:||||..:.|....|||||||..|||.
  Fly   492 SILLAADGRVKLSDFGFCAQVSQELPKRKSLVGTPYWMSPEVISRLPYGPEVDIWSLGIMVIEMV 556

Human   219 EGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRS 283
            :|:||:.:..|::|:..|....||..:.....|.....|:.:.||:.|.|||||.:||.|||:|.
  Fly   557 DGEPPFFNEPPLQAMRRIRDMQPPNLKNAHKVSPRLQSFLDRMLVRDPAQRATAAELLAHPFLRQ 621

Human   284 AKGVSILRDLINEA 297
            |...|:|..|:..|
  Fly   622 AGPPSLLVPLMRNA 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STK4	NP_006273.1	STKc_MST1_2	26..281	CDD:132943	104/256 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	303..332
		SARAH_MST1	432..480	CDD:439181
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526
		STKc_PAK_II	360..620	CDD:270815	105/257 (41%)